A Study of JNJ-88998377 for Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma
Last Updated May 29, 2025
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88998377LYM1001
OVERVIEW
-
Sexes Eligible for Study
all -
Age
years -
Phase
phase 1 -
Sites
Sites -
Status
Recruiting
SUMMARY
The main purpose of this study is to characterize safety and to determine the recommended phase 2 dose (RP2D) for JNJ-88998377 (Part A: Dose Escalation) and to further assess the safety of JNJ-88998377 at the RP2D (Part B: Dose Expansion).
CONDITIONS
- Lymphoma, Non-Hodgkin
- Refractory B-Cell NHL
- Relapsed B-cell NHL
ELIGIBILITY
Inclusion Criteria:
* Participants have histologically or cytologically confirmed B-cell non-Hodgkin's Lymphoma (NHL) according to the 2022 World Health Organization (WHO) classification with relapsed or refractory disease
* Participants have measurable disease or meet all requir
DETAILS
LOCATIONS
| Country (7) | City or Province (19) | Status |
| Japan | Tokyo The Cancer Institute Hospital of JFCR |
RECRUITING
|
| Taiwan | Taipei National Taiwan University Hospital |
RECRUITING
|
| Taiwan | Taoyuan Linkou Chang Gung Memorial Hospital |
RECRUITING
|
| Türkiye | Ankara Dr Abdurrahman Yurtaslan Oncology Training and Research Hospital |
RECRUITING
|
| Türkiye | Ankara Ankara University Medical Faculty |
RECRUITING
|
| Türkiye | Istanbul Koc University Medical Faculty |
RECRUITING
|
| Italy | Bologna A O U Sant Orsola Malpighi |
RECRUITING
|
| South Korea | Seoul Samsung Medical Center |
RECRUITING
|
| China | Beijing Beijing Cancer Hospital |
RECRUITING
|
| China | Hang Zhou Shi The First Affiliated Hospital Zhejiang University College of Medicine |
RECRUITING
|
| China | Shanghai Fudan University Shanghai Cancer Center |
RECRUITING
|
| China | Tianjin Tianjin Medical University Cancer Institute and Hospital |
RECRUITING
|
| Japan | Kashiwa National Cancer Center Hospital East |
RECRUITING
|
| South Korea | Seoul Seoul National University Hospital |
RECRUITING
|
| Poland | Katowice Pratia Onkologia Katowice |
RECRUITING
|
| Poland | Kielce Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach, Klinika Hematologii i Transplantacji Szpiku |
RECRUITING
|
| Poland | Skorzewo Aidport Sp z o o |
RECRUITING
|
| China | Guangzhou Sun Yat Sen University Cancer Center |
RECRUITING
|
| Japan | Chuo Ku National Cancer Center Hospital |
COMPLETED
|
35.6895, 139.69171
25.04776, 121.53185
24.95233, 121.20193
39.91987, 32.85427
39.91987, 32.85427
41.01384, 28.94966
44.49381, 11.33875
37.566, 126.9784
39.9075, 116.39723
30.2341099, 120.164
31.22222, 121.45806
39.14222, 117.17667
35.86224, 139.97732
37.566, 126.9784
50.25841, 19.02754
50.87033, 20.62752
52.3906266, 16.7919124
23.11667, 113.25
35.57779, 139.71685
Indicates 50+ sites in this region: click to zoom in.
Indicates 10+ sites in this region: click to zoom in.
Indicates < 10 sites in this region: click to zoom in.
Corresponds to individual site.