Clinical Trials
Helping Others by Contributing to Medical Research
All about clinical trials
- Clinical trial overview
- Terms you should know
- Phases of clinical trial
- Diversity in trials
- Patient Perspective(s)
Phases of a clinical trial
ONE
Phase I
The investigational medication or vaccine is evaluated in a small group of people for the first time to gather information on its safety, dosing, and side effects.
TWO
Phase II
The investigational medication or vaccine is evaluated in a larger group of patients to see if it is effective and to better understand its safety.
THREE
Phase III
The investigational medication or vaccine is given to a large group of patients to evaluate its effectiveness, compare it to commonly used medications (known as standard of care) or placebo, and collect information regarding the safety of the investigational medication.
FOUR
Phase IV
Phase IV trials are conducted after a medication or vaccine has been approved by a country’s regulatory medical authorities. The purpose of these trials is to gather more information on the medication or vaccine’s effects and side effects.