A Study of TAR-200 Versus Intravesical Chemotherapy in Participants With Recurrent High-Risk Non-Muscle-Invasive Bladder Cancer (HR-NMIBC) After Bacillus Calmette-Guérin (BCG) (SunRISe-5)
Last Updated January 11, 2025
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17000139BLC3004
OVERVIEW
-
Sexes Eligible for Study
all -
Age
years -
Phase
phase 33 -
Sites
Sites -
Status
Recruiting
SUMMARY
The purpose of this study is to compare disease free survival (DFS) in participants with recurrence of papillary-only high-risk non-muscle-invasive bladder cancer (HR-NMIBC) within 1 year of last dose of Bacillus Calmette-Guérin (BCG) therapy and who refused or are unfit for Radical Cystectomy (RC), receiving TAR-200 versus investigator's choice of single agent intravesical chemotherapy.
CONDITIONS
- Non-Muscle Invasive Bladder Neoplasms
ELIGIBILITY
Inclusion Criteria:
* Histologically confirmed diagnosis by local pathology (within 90 days of documented informed consent) of recurrent, papillary-only high-risk non-muscle-invasive bladder cancer (HR-NMIBC) [defined as high-grade Ta or any T1, no carcinoma in situ (CIS)]
* Part
DETAILS
LOCATIONS
Locations in:
United States, Argentina, Belgium, Brazil, China, France, Germany, Italy, Japan, South Korea, Poland, Romania, Spain, United Kingdom
| Country (14) | City or Province (98) | Status |
| United States | Little Rock Arkansas Urology |
RECRUITING
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| United States | Los Alamitos Genesis Research LLC |
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| United States | Orange University of California Irvine Medical Center |
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| United States | Torrance Genesis Research LLC |
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| United States | Lakewood Colorado Clinical Research |
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| United States | Riverview Florida Urology Partners |
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| United States | Chicago Ridge UroPartners |
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| United States | Carmel Urology of Indiana |
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| United States | Jeffersonville First Urology, PSC |
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| United States | Wichita Wichita Urology Group |
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| United States | Royal Oak Comprehensive Urology |
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| United States | Saint Louis Specialty Clinical Research of St Louis |
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| United States | Syracuse Associated Medical Professionals |
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| United States | Cincinnati The Urology Group |
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| United States | Gahanna Central Ohio Urology Group |
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| United States | Bala-Cynwyd Centers for Advanced Urology LLC d b a MidLantic Urology |
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| United States | Myrtle Beach Carolina Urologic Research Center |
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| United States | North Charleston Low Country Urology Clinics |
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| United States | Nashville Urology Associates |
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| United States | Austin Urology Austin |
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| United States | Dallas Urology Clinics of North Texas |
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| United States | Houston Houston Metro Urology |
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| United States | Spokane Spokane Urology |
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| Argentina | Buenos Aires Clinica Santa Isabel |
RECRUITING
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| Argentina | Caba Investigaciones Clinico Moleculares (ICM) |
RECRUITING
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| Argentina | Cordoba Cemaic Centro Privado de Especialidades Medicas Ambulatorias e Investigacion Clinica |
RECRUITING
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| Argentina | Córdoba Centro Urologico Profesor Bengio |
RECRUITING
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| Argentina | Mar del Plata Hospital Privado de la Comunidad |
RECRUITING
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| Belgium | Brugge AZ Sint-Jan |
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| Belgium | Genk Ziekenhuis Oost-Limburg |
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| Belgium | Gent Algemeen ziekenhuis Maria Middelares |
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| Belgium | Roeselare Algemeen Ziekenhuis Delta |
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| Brazil | Barretos Fundacao Pio XII |
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| Brazil | Bauru NAIC Nair Antunes Instituto do Cancer |
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| Brazil | Curitiba Liga Paranaense de Combate ao Cancer |
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| Brazil | Porto Alegre Irmandade Santa Casa de Misericordia de Porto Alegre |
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| Brazil | Sao Paulo Real e Benemérita Associação Portuguesa de Beneficência |
RECRUITING
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| Brazil | Sao Paulo Fundacao Antonio Prudente A C Camargo Cancer Center |
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| China | Beijing Peking University First Hospital |
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| China | Cheng Du Shi West China School of Medicine/West China Hospital, Sichuan University |
RECRUITING
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| China | Chong Qing Chongqing Cancer Hospital |
RECRUITING
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| China | Guang Zhou Shi Sun Yat-Sen University Cancer Center |
RECRUITING
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| China | Shen Yang Shi Shengjing Hospital Of China Medical University |
RECRUITING
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| China | Tianjin Tianjin Medical University Cancer Institute and Hospital |
RECRUITING
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| China | Tianjin The Second Hospital Of Tianjin Medical University |
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| China | Wenzhou The First Affiliated Hospital of Wenzhou Medical University |
RECRUITING
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| China | Wuhan Tongji Medical College of Huazhong University Science Technology of Medicine Health Management |
RECRUITING
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| China | XI An Shi Xi an Jiaotong University Hospital |
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| France | Limoges Polyclinique de Limoges - Francois Chenieux |
RECRUITING
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| France | Paris APHP - Hopital Bichat - Claude Bernard |
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| France | Quint-Fonsegrives Clinique de la Croix du Sud |
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| France | Suresnes Hopital Foch |
RECRUITING
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| Germany | Halle (Saale) Universitaetsklinikum Halle Saale |
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| Germany | Köln Universitaetsklinikum Koeln |
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| Germany | Leverkusen Klinikum Leverkusen gGmbH |
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| Germany | Lubeck Universitatsklinikum Schleswig Holstein Campus Lubeck |
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| Germany | Mettmann Urologie Neandertal Praxis Mettmann |
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| Germany | Munchen Klinikum der Universitaet Muenchen |
RECRUITING
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| Italy | Arezzo Ospedale San Donato |
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| Italy | Ravenna Ospedale S. Maria Delle Croci |
RECRUITING
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| Italy | Roma Istituto Nazionale Tumori Regina Elena |
RECRUITING
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| Italy | Rozzano Istituto Clinico Humanitas |
RECRUITING
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| Italy | Torino PO Molinette Azienda Ospedaliero Universitaria Citta della Salute e della Scienza di Torino |
RECRUITING
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| Japan | Chiba Funabashi Munitiple Medical Center |
RECRUITING
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| Japan | Hakodate Hakodate Goryoukaku Hospital |
RECRUITING
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| Japan | Hyogo Hyogo Prefectural Amagasaki General Medical Center |
RECRUITING
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| Japan | Niigata Niigata Cancer Center Hospital |
RECRUITING
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| Japan | Okayama National Hospital Organization Okayama Medical Center |
RECRUITING
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| Japan | Sakura Toho University Sakura Medical Center |
RECRUITING
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| Japan | Tokyo Toranomon Hospital |
RECRUITING
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| Japan | Yokohama Yokohama City University Medical Center |
RECRUITING
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| South Korea | Chungcheongbuk Do Chungbuk National University Hospital |
RECRUITING
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| South Korea | Daegu Keimyung University Dongsan Hospital |
RECRUITING
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| South Korea | Gyeonggi-do National Cancer Center |
RECRUITING
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| South Korea | Jeollanam-do Chonnam National University Hwasun Hospital |
RECRUITING
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| South Korea | Seoul Seoul National University Hospital |
RECRUITING
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| South Korea | Seoul Samsung Medical Center |
RECRUITING
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| South Korea | Seoul The Catholic University of Korea Seoul St Mary s Hospital |
RECRUITING
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| South Korea | Yangsan-si Pusan National University Yangsan Hospital |
RECRUITING
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| Poland | Bialystok Uniwersytecki Szpital Kliniczny w Bialymstoku |
RECRUITING
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| Poland | Bydgoszcz IN VIVO Sp. z o.o |
RECRUITING
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| Poland | Przemysl Wojewodzki Szpital im Sw Ojca Pio w Przemyslu |
RECRUITING
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| Poland | Tarnow Szpital Wojewodzki im. Sw. Lukasza SP ZOZ |
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| Poland | Torun MICS Centrum Medyczne Torun |
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| Poland | Wieliszew Mazowiecki Szpital Onkologiczny |
RECRUITING
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| Poland | Wroclaw Dolnoslaskie Centrum Onkologii |
RECRUITING
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| Romania | Brasov Centrul Medical Unirea SRL |
RECRUITING
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| Romania | Bucuresti Ponderas Academic Hospital |
RECRUITING
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| Romania | Cluj-Napoca Institutul Oncologic Ion Chiricuta |
RECRUITING
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| Romania | Cluj-Napoca Regina Maria |
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| Romania | Timisoara Spitalul Clinic Judetean de Urgenta Pius Brinzeu |
RECRUITING
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| Spain | Madrid Hosp. Univ. 12 de Octubre |
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| Spain | Málaga Hosp Virgen de La Victoria |
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| Spain | Sabadell Hosp.Univ.Parc Tauli |
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| United Kingdom | London St Bartholomews Hospital |
RECRUITING
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| United Kingdom | Salford Salford Royal Hospital |
RECRUITING
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| United Kingdom | Southampton Southampton University Hospital |
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| United Kingdom | Stevenage Lister Hospital |
RECRUITING
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Geo Locations
34.74648, -92.28959
33.80307, -118.07256
33.78779, -117.85311
33.83585, -118.34063
39.70471, -105.08137
27.86614, -82.32648
41.70142, -87.77922
39.97837, -86.11804
38.27757, -85.73718
37.69224, -97.33754
42.48948, -83.14465
38.62727, -90.19789
43.04812, -76.14742
39.12713, -84.51435
40.01923, -82.87934
40.00761, -75.23407
33.68906, -78.88669
32.85462, -79.97481
36.16589, -86.78444
30.26715, -97.74306
32.78306, -96.80667
29.76328, -95.36327
47.65966, -117.42908
-34.61315, -58.37723
-34.61315, -58.37723
-31.4135, -64.18105
-31.4135, -64.18105
-38.00228, -57.55754
51.20892, 3.22424
50.965, 5.50082
51.05, 3.71667
50.94653, 3.12269
-20.55722, -48.56778
-22.31472, -49.06056
-25.42778, -49.27306
-30.03306, -51.23
-23.5475, -46.63611
-23.5475, -46.63611
39.9075, 116.39723
30.5970699, 104.05106
29.6433899, 106.45187
23.1323999, 113.288
41.7822799, 123.42179
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34.2075699, 108.94631
45.83153, 1.25781
48.85341, 2.3488
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51.48159, 11.97948
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51.0303, 6.98432
53.86893, 10.68729
51.2504, 6.97536
48.13743, 11.57549
43.46276, 11.88068
44.41344, 12.20121
41.89193, 12.51133
45.38193, 9.1559
45.07049, 7.68682
35.6, 140.11667
41.77583, 140.73667
34.7300449, 135.4133985
37.88637, 139.00589
34.65, 133.93333
35.71667, 140.23333
35.6895, 139.69171
35.43333, 139.65
36.6266068, 127.4570629
35.87028, 128.59111
37.58944, 126.76917
35.056264, 127.0025403
37.566, 126.9784
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37.566, 126.9784
35.3251513, 129.0068369
53.13333, 23.16433
53.1235, 18.00762
49.78498, 22.76728
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51.1, 17.03333
45.64861, 25.60613
44.42802, 26.09665
46.76667, 23.6
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45.75372, 21.22571
40.4165, -3.70256
36.72016, -4.42034
41.54329, 2.10942
51.50853, -0.12574
53.48771, -2.29042
50.90395, -1.40428
51.90224, -0.20256
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