A Study Comparing Pre- and Post-Change Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma (MajesTEC-10)

Last Updated   January 18, 2025

Want to learn how to participate in this trial?

64007957MMY1008

OVERVIEW

  • Sexes Eligible for Study
    all
  • Age
    18+ years
  • Phase
    phase 1
    1
  • Sites
    29 Sites
  • Status
     Recruiting

SUMMARY

The purpose of this study is to compare the pharmacokinetics (processes by which drugs are absorbed, distributed in the body, and excreted) between teclistamab made from the current commercial manufacturing process (pre-change) and the new manufacturing process (post-change).

CONDITIONS

  • Relapsed or Refractory Multiple Myeloma

ELIGIBILITY


Inclusion Criteria:

* Documented diagnosis of multiple myeloma as defined by the criteria below: (a) Multiple myeloma diagnosis according to International Myeloma Working Group (IMWG) diagnostic criteria (b) Measurable disease at screening as defined by any of the following: (1) Ser

More...

DETAILS

LOCATIONS

Locations in:
United States, Australia, France, Italy, South Korea, Poland, Spain, United Kingdom
Country (8) City or Province (29) Status
United States Denver Colorado Blood Cancer Institute
RECRUITING
United States Weston Cleveland Clinic Florida
RECRUITING
United States Augusta Augusta University- Georgia Cancer Center
RECRUITING
United States Cleveland Cleveland Clinic
RECRUITING
United States Dallas Baylor University Medical Center
RECRUITING
Australia Box Hill Box Hill Hospital
RECRUITING
Australia Camperdown Royal Prince Alfred Hospital
RECRUITING
Australia Richmond Epworth Healthcare
RECRUITING
France Nantes Cedex 1 CHU Nantes
RECRUITING
France Pessac Cedex CHU de Bordeaux - Hospital Haut-Leveque
RECRUITING
Italy Brescia Azienda Ospedaliera Spedali Civili di Brescia
RECRUITING
Italy Meldola Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori
RECRUITING
Italy Rome Policlinico Universitario Agostino Gemelli
RECRUITING
South Korea Seoul Seoul National University Hospital
RECRUITING
South Korea Seoul Severance Hospital Yonsei University Health System
RECRUITING
South Korea Seoul Asan Medical Center
RECRUITING
South Korea Seoul Samsung Medical Center
RECRUITING
South Korea Seoul The Catholic University of Korea Seoul St Mary s Hospital
RECRUITING
Poland Gdansk Uniwersyteckie Centrum Kliniczne
RECRUITING
Poland Katowice Pratia Onkologia Katowice
RECRUITING
Poland Kielce Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach
RECRUITING
Poland Lublin Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli
RECRUITING
Spain Madrid Hosp. Univ. 12 de Octubre
RECRUITING
Spain Pamplona Clinica Univ. de Navarra
RECRUITING
Spain Pozuelo de Alarcon Hosp. Quiron Madrid Pozuelo
RECRUITING
Spain Salamanca Hosp Clinico Univ de Salamanca
RECRUITING
Spain Santander Hosp. Univ. Marques de Valdecilla
RECRUITING
United Kingdom London Hammersmith Hospital
RECRUITING
United Kingdom Plymouth Derriford Hospital
RECRUITING
Show More
Geo Locations

39.73915, -104.9847

26.10037, -80.39977

33.47097, -81.97484

41.4995, -81.69541

32.78306, -96.80667

-37.81887, 145.12545

-33.88965, 151.17642

-37.81819, 145.00176

47.21725, -1.55336

44.81011, -0.64129

45.53558, 10.21472

44.12775, 12.0626

41.89193, 12.51133

37.566, 126.9784

37.566, 126.9784

37.566, 126.9784

37.566, 126.9784

37.566, 126.9784

54.35205, 18.64637

50.25841, 19.02754

50.87033, 20.62752

51.25, 22.56667

40.4165, -3.70256

42.81687, -1.64323

40.43293, -3.81338

40.96882, -5.66388

43.46472, -3.80444

51.50853, -0.12574

50.37153, -4.14305

x
50

Indicates 50+ sites in this region: click to zoom in.

10

Indicates 10+ sites in this region: click to zoom in.

5

Indicates < 10 sites in this region: click to zoom in.

Corresponds to individual site.

Interested in participating?