A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease (Reτain)
Last Updated August 30, 2024
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64042056ALZ2001
OVERVIEW
-
Sexes Eligible for Study
all -
Age
years -
Phase
phase 22 -
Sites
Sites -
Status
Recruiting
SUMMARY
The purpose of this study is to assess the effect of JNJ-64042056 on cognitive decline, as measured by Preclinical Alzheimer's disease Cognitive Composite 5 (PACC-5) compared with placebo.
CONDITIONS
- Preclinical Alzheimer's Disease
ELIGIBILITY
Inclusion Criteria:
* Elevated brain tau pathology defined as Braak 3 region of interest standardized uptake value ratio (ROI SUVR) greater than (>) 1.1 on a screening tau PET scan, reviewed centrally by a qualified reader
* Clinical Dementia Rating (CDR) global score of 0 at scr
DETAILS
LOCATIONS
| Country (2) | City or Province (21) | Status |
| United States | Riverside Artemis Institute for Clinical Research |
RECRUITING
|
| United States | San Diego Artemis Institute for Clinical Research |
RECRUITING
|
| United States | Atlantis JEM Research LLC |
RECRUITING
|
| United States | Clermont K2 Medical Research Winter Garden |
RECRUITING
|
| United States | Maitland K2 Medical Research |
RECRUITING
|
| United States | Merritt Island Merritt Island Medical Research, LLC |
RECRUITING
|
| United States | Orlando Headlands Research Orlando |
RECRUITING
|
| United States | Stuart Alzheimers Research and Treatment Center |
RECRUITING
|
| United States | The Villages Charter Research |
RECRUITING
|
| United States | The Villages K2 Medical Research |
RECRUITING
|
| United States | Wellington Alzheimers Research and Treatment Center |
RECRUITING
|
| United States | Hattiesburg Hattiesburg Clinic |
RECRUITING
|
| United States | East Syracuse Velocity Clinical Research |
RECRUITING
|
| United States | Centerville Valley Medical Research |
RECRUITING
|
| United States | Plymouth Meeting Keystone Clinical Studies LLC |
RECRUITING
|
| Japan | Chuo-ku Tokyo Asbo Clinic |
RECRUITING
|
| Japan | Hirakata-shi Hatsuta Neurology Clinic |
RECRUITING
|
| Japan | Kobe Kusunoki Clinic |
RECRUITING
|
| Japan | Shinjuku-ku Medical Corporation Heishinkai ToCROM Clinic |
RECRUITING
|
| Japan | Suita-shi Medical Corporation Heishinkai OCROM Clinic |
RECRUITING
|
| Japan | Toyonaka-shi Nagomi Clinic |
RECRUITING
|
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