A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease (Reτain)
Last Updated May 14, 2025
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64042056ALZ2001
OVERVIEW
-
Sexes Eligible for Study
all -
Age
years -
Phase
phase 22 -
Sites
Sites -
Status
Recruiting
SUMMARY
The purpose of this study is to assess the effect of JNJ-64042056 on cognitive decline, as measured by Preclinical Alzheimer's disease Cognitive Composite 5 (PACC-5) compared with placebo.
CONDITIONS
- Preclinical Alzheimer's Disease
ELIGIBILITY
Inclusion Criteria:
* Elevated brain tau pathology defined as Braak 3 region of interest standardized uptake value ratio (ROI SUVR) greater than (>) 1.1 on a screening tau PET scan, reviewed centrally by a qualified reader
* Clinical Dementia Rating (CDR) global score of 0 at scr
DETAILS
LOCATIONS
Locations in:
United States, Japan, Australia, France, Spain, Sweden, United Kingdom
| Country (7) | City or Province (75) | Status |
| United States | Riverside Artemis Institute for Clinical Research |
RECRUITING
|
| United States | San Diego Artemis Institute for Clinical Research |
RECRUITING
|
| United States | Atlantis JEM Research LLC |
RECRUITING
|
| United States | Clermont K2 Medical Research Winter Garden |
RECRUITING
|
| United States | Maitland K2 Medical Research |
RECRUITING
|
| United States | Merritt Island Merritt Island Medical Research, LLC |
RECRUITING
|
| United States | Orlando Headlands Research Orlando |
RECRUITING
|
| United States | Stuart Alzheimers Research and Treatment Center |
RECRUITING
|
| United States | Wellington Alzheimers Research and Treatment Center |
RECRUITING
|
| United States | Hattiesburg Hattiesburg Clinic |
RECRUITING
|
| United States | East Syracuse Velocity Clinical Research |
RECRUITING
|
| United States | Centerville Valley Medical Research |
RECRUITING
|
| United States | Plymouth Meeting Keystone Clinical Studies LLC |
RECRUITING
|
| Japan | Chuo-ku Tokyo Asbo Clinic |
RECRUITING
|
| Japan | Hirakata-shi Hatsuta Neurology Clinic |
RECRUITING
|
| Japan | Kobe Kusunoki Clinic |
RECRUITING
|
| Japan | Toyonaka-shi Nagomi Clinic |
RECRUITING
|
| United States | Phoenix Xenoscience Inc. |
RECRUITING
|
| United States | Irvine Irvine Clinical Research |
RECRUITING
|
| United States | Boca Raton Excel Medical Clinical Trials, LLC |
RECRUITING
|
| United States | Jacksonville Clinical NeuroScience Solutions Inc |
RECRUITING
|
| United States | Lady Lake K2 Medical Research |
RECRUITING
|
| United States | Tampa K2 Medical Research |
RECRUITING
|
| United States | The Villages Charter Research |
RECRUITING
|
| United States | West Palm Beach Palm Beach Neurology and Premier Research Institute |
RECRUITING
|
| United States | Chicago Great Lakes Clinical Trials |
RECRUITING
|
| United States | Gurnee Great Lakes Clinical Trials |
RECRUITING
|
| United States | Farmington Hills Quest Research Institute |
RECRUITING
|
| United States | Springfield The Cognitive and Research Center of New Jersey LLC |
RECRUITING
|
| United States | Albany Neurological Associates of Albany, PC |
RECRUITING
|
| United States | New York The Medical Research Network, LLC |
RECRUITING
|
| United States | Matthews AMC Research, LLC |
RECRUITING
|
| United States | Providence Butler Hospital |
RECRUITING
|
| United States | San Antonio Clinical Trials of Texas Inc |
RECRUITING
|
| United States | Bennington Memory Clinic Inc |
RECRUITING
|
| United States | Charlottesville University of Virginia |
RECRUITING
|
| Australia | Carlton Neuro Trials Victoria |
RECRUITING
|
| Australia | Chermside The Prince Charles Hospital |
RECRUITING
|
| Australia | Darlinghurst St Vincent's Centre for Applied Medical Research |
RECRUITING
|
| Australia | Ivanhoe Austin Health Heidelberg Repatriation Hospital |
RECRUITING
|
| Australia | Kogarah Southern Neurology |
RECRUITING
|
| Australia | Macquarie Park KaRa Institute of Neurological Diseases |
RECRUITING
|
| Australia | Nedlands Australian Alzheimer's Research Foundation Incorporated |
RECRUITING
|
| France | Toulouse CHU Toulouse - Hôpital La Grave |
RECRUITING
|
| Japan | Chofu-shi Enomoto Internal Medicine Clinic |
RECRUITING
|
| Japan | Kobe City Kobe City Medical Center General Hospital |
RECRUITING
|
| Japan | Musashimurayama Musashimurayama Hospital |
RECRUITING
|
| Japan | Narashino-shi Saiseikai Narashino Hospital |
RECRUITING
|
| Japan | Shinjuku ku ToCROM Clinic |
RECRUITING
|
| Japan | Shinjuku-ku Higashi-Shinjuku Clinic |
RECRUITING
|
| Japan | Shinjyuku Ku Medical corporation Shinanokai Samoncho Clinic |
RECRUITING
|
| Japan | Suita shi OCROM Clinic |
RECRUITING
|
| Spain | Barcelona Barcelona Beta Brain Research Center |
RECRUITING
|
| Spain | Barcelona Hosp Clinic de Barcelona |
RECRUITING
|
| Spain | Getxo Centro At. Esp. Oroitu |
RECRUITING
|
| Spain | Madrid Hosp. Clinico San Carlos |
RECRUITING
|
| Spain | Pamplona Clinica Univ. de Navarra |
RECRUITING
|
| Spain | Pozuelo de Alarcón Hosp. Quiron Madrid Pozuelo |
RECRUITING
|
| Spain | Terrassa Hosp. Mutua Terrassa |
RECRUITING
|
| Spain | Zaragoza Hosp. Viamed Montecanal |
RECRUITING
|
| Sweden | Stockholm Karolinska Universitetssjukhuset Huddinge |
RECRUITING
|
| United Kingdom | Bath Royal United Hospital |
RECRUITING
|
| United Kingdom | Birmingham Re-Cognition Health |
RECRUITING
|
| United Kingdom | Bristol Re-Cognition Health |
RECRUITING
|
| United Kingdom | Guildford Re-Cognition Health |
RECRUITING
|
| United Kingdom | London Re-Cognition Health |
RECRUITING
|
| United Kingdom | London Kings College Hospital |
RECRUITING
|
| United Kingdom | Oxford University of Oxford |
RECRUITING
|
| United Kingdom | Plymouth Re-Cognition Health |
RECRUITING
|
| United Kingdom | Southampton Moorgreen Hospital Memory Assessment And Research Centre |
RECRUITING
|
| United Kingdom | Southampton Southampton General Hospital |
RECRUITING
|
| United Kingdom | Winchester Re-Cognition Health |
RECRUITING
|
| Japan | Toyonaka-shi Jinsenkai MI Clinic |
RECRUITING
|
| Spain | Barcelona Fund. Ace-Inst. Cat. Neuroc. Aplicades |
RECRUITING
|
| United Kingdom | Edinburgh Scottish Brain Sciences |
RECRUITING
|
Geo Locations
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-27.38472, 153.03062
-33.87939, 151.21925
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34.78244, 135.46932
41.38879, 2.15899
55.95206, -3.19648
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