A Study of Aticaprant Plus an Antidepressant to Prevent Return of Depression Symptoms in Participants With Major Depressive Disorder Who Experience a Loss of Interest and Pleasure (VENTURA-5)
Last Updated February 21, 2025
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67953964MDD3005
OVERVIEW
-
Sexes Eligible for Study
all -
Age
years -
Phase
phase 33 -
Sites
Sites -
Status
Recruiting
SUMMARY
The purpose of this study is to assess how well aticaprant works compared to placebo when given in addition to antidepressant therapy (selective serotonin reuptake inhibitor [SSRI] or serotonin-norepinephrine reuptake inhibitor [SNRI]) in preventing return of depression symptoms in participants with major depressive disorder who experience a loss of interest and pleasure and who achieve a stable response after treatment with adjunctive aticaprant.
CONDITIONS
- Depressive Disorder, Major
- Anhedonia
ELIGIBILITY
Inclusion Criteria:
* Be medically stable based on physical examination (including a brief neurologic examination), medical history, vital signs (including blood pressure), and 12-lead electrocardiogram (ECG) performed at screening and OL baseline
* Be medically stable based on c
DETAILS
LOCATIONS
| Country (6) | City or Province (33) | Status |
| United States | Redlands Myndful Research |
RECRUITING
|
| United States | San Diego Artemis Institute for Clinical Research |
RECRUITING
|
| United States | Doral UHC Research |
RECRUITING
|
| United States | Miami International Research Associates, LLC |
RECRUITING
|
| United States | North Miami Beach Harmony Clinical Research Inc |
RECRUITING
|
| United States | Tampa Interventional Psychiatry of Tampa Bay |
RECRUITING
|
| United States | Atlanta Synexus Clinical Research US Inc |
RECRUITING
|
| United States | Chicago Chicago Research Center |
RECRUITING
|
| United States | Skokie Psychiatric Medicine Associates LLC |
RECRUITING
|
| United States | Towson Continental Clinical Solutions |
RECRUITING
|
| United States | Albuquerque IMA Clinical Research PC |
RECRUITING
|
| United States | Brooklyn Integrative Clinical Trials LLC |
RECRUITING
|
| United States | Mount Kisco Bioscience Research LLC |
RECRUITING
|
| United States | Independence Insight Clinical Trials |
RECRUITING
|
| United States | Tulsa Laureate Institute for Brain Research |
RECRUITING
|
| United States | Plymouth Meeting Keystone Clinical Studies LLC |
RECRUITING
|
| United States | North Charleston Coastal Carolina Research Center |
RECRUITING
|
| United States | DeSoto InSite Clinical Research LLC |
RECRUITING
|
| United States | Friendswood Earle Research |
RECRUITING
|
| United States | Clinton Alpine Research Organization |
RECRUITING
|
| Argentina | Ciudad Autonoma de Buenos Aires Hospital Italiano de Buenos Aires |
RECRUITING
|
| Argentina | Cordoba Centro Medico Instituto Modelo de Neurologia y Neurorehabilitacion |
RECRUITING
|
| Germany | Chemnitz Pharmakologisches Studienzentrum Chemnitz GmbH |
RECRUITING
|
| Germany | Hamburg Klinische Forschung Hamburg |
RECRUITING
|
| Germany | Rosenheim Boehm Peters Praxis fur Psychiatrie Psychotherapie Neurologie PartGmbB |
RECRUITING
|
| Mexico | Leon Hospital Aranda de la Parra S A de C V |
RECRUITING
|
| Mexico | Mexico city Ketamine Mexico S de RL de C V |
RECRUITING
|
| Mexico | Mexico Human Science Research Trials S de RL de CV |
RECRUITING
|
| Mexico | Monterrey cit NEUROPSIQUE |
RECRUITING
|
| Poland | Lublin Centrum Medyczne Luxmed Sp z o o |
RECRUITING
|
| Poland | Warszawa Care Access Warszawa |
RECRUITING
|
| Poland | Warszawa MTZ Clinical Research Powered by Pratia |
RECRUITING
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| Romania | Bucuresti Centrul de Evaluarea si Tratament al Toxicodependentelor pentru Tineri Sf. Stelian |
RECRUITING
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