A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
Last Updated   April 25, 2024 - 21:08
OVERVIEW
-
Gender
all -
Age
years -
Phase
phase 3The drug or treatment is given to large groups of people to confirm its effectiveness, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely. -
Sites
sites -
Status
Recruiting
SUMMARY
The purpose of the study is to see how effective JNJ-77242113 is in participants with moderate to severe plaque psoriasis compared to placebo and deucravacitinib.
CONDITIONS
- plaque psoriasis
ELIGIBILITY
Inclusion Criteria:
* Diagnosis of plaque psoriasis, with or without psoriatic arthritis (PsA), for at least 26 weeks prior to the first administration of study intervention
* Total body surface area (BSA) greater than or equal to (>=)10 percent (%) at screening and baseline
* Total psoriasis area and severity index (PASI) >=12 at screening and baseline
* Total investigator global assessment (IGA) >=3 at screening and baseline
* Candidate for phototherapy or systemic treatment for plaque psoriasis
Exclusion Criteria:
* Nonplaque form of psoriasis (for example, erythrodermic, guttate, or pustular)
* Current drug-induced psoriasis (for example, a new onset of psoriasis or an exacerbation of psoriasis from beta blockers, calcium channel blockers, or lithium)
* A current diagnosis or signs or symptoms of severe, progressive, or uncontrolled renal, liver, cardiac, vascular, pulmonary, gastrointestinal, endocrine, neurologic, hematologic, rheumatologic, psychiatric, or metabolic disturbances
* Known allergies, hypersensitivity, or intolerance to JNJ-77242113, deucravacitinib, or to any of the excipients or components of the study intervention
* Major surgical procedure, (for example, requiring general anesthesia) within 8 weeks before screening, or will not have fully recovered from surgical procedure, or has a surgical procedure planned during the time the participant is expected to participate in the study
DETAILS
LOCATIONS
Country (13) | City or Province (164) | Status |
United States | Alpharetta, GA Hamilton Research, LLC. |
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United States | Ann Arbor, MI David Fivenson MD, Dermatology |
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United States | Athens, OH Oakview Dermatology |
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United States | Boardman, OH Optima Research |
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United States | Boston, MA Tufts Medical Center |
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United States | Chicago, IL Illinois Dermatology Institute - Chicago Loop Office |
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United States | Clarkston, MI Michigan Center of Medical Research |
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United States | Coral Gables, FL Driven Research LLC |
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United States | Dallas, TX Modern Research Associates |
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United States | Detroit, MI Henry Ford Medical Center |
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United States | East Windsor, NJ Windsor Dermatology |
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United States | Fort Gratiot, MI Hamzavi Dermatology |
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United States | Fort Smith, AR Johnson Dermatology |
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United States | Fountain Valley, CA First OC Dermatology |
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United States | Fremont, CA Center for Dermatology Clinical Research |
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United States | Hackensack, NJ Schweiger Dermatology Group |
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United States | Houston, TX Austin Institute for Clinical Research |
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United States | Houston, TX Center for Clinical Studies |
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United States | Indianapolis, IN Dawes Fretzin Clinical Research Group, LLC |
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United States | Lake Charles, LA Dermatology and Advanced Aesthetics |
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United States | Las Vegas, NV Fife Dermatology |
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United States | Louisville, KY Dermatology Specialists |
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United States | Macon, GA Skin Care Physicians of Georgia |
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United States | Mill Creek, WA Frontier Derm Partners CRO, LLC |
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United States | North Miami Beach, FL Ziaderm Research, LLC |
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United States | Ocala, FL Renstar Medical Research |
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United States | Oklahoma City, OK Central Sooner Research |
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United States | Omaha, NE Skin Specialists |
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United States | Pflugerville, TX Austin Institute for Clinical Research |
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United States | Phoenix, AZ Medical Dermatology Specialists |
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United States | Plainfield, IN Indiana Clinical Trial Center |
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United States | Portland, OR Oregon Medical Research Center |
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United States | Portsmouth, NH Allcutis Research |
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United States | Rapid City, SD Health Concepts |
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United States | Richmond, VA National Clinical Research |
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United States | Rolling Meadows, IL Arlington Dermatology |
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United States | Sacramento, CA Integrative Skin Science and Research |
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United States | Saint Joseph, MO MediSearch Clinical Trials |
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United States | San Antonio, TX Progressive Clinical Research |
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United States | San Antonio, TX Texas Dermatology and Laser Specialists |
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United States | Santa Ana, CA Southern California Dermatology |
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United States | Santa Monica, CA Clinical Science Institute |
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United States | Scottsdale, AZ Center for Dermatology and Plastic Surgery |
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United States | Skokie, IL Northshore Medical Group |
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United States | Spokane, WA Premier Clinical Research |
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United States | Stony Brook, NY Derm Research Center of New York, Inc. |
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United States | Tampa, FL Forcare Clinical Research Inc |
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United States | Webster, TX Center for Clinical Studies |
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United States | West Dundee, IL Dundee Dermatology |
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United States | Wilmington, NC Wilmington Dermatology Center |
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United Kingdom | London Guy's and St Thomas' NHS Foundation Trust |
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United Kingdom | Reading, BRK Royal Berkshire Hospital |
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United Kingdom | Salford Salford Royal Hospital |
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United Kingdom | Southampton University Hospital Southampton NHS Foundation Trust |
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Taiwan | Hsin Chu National Taiwan University Hospital Hsin-Chu Branch |
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Taiwan | Kaohsiung City Chang Kung Memorial Hospital |
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Taiwan | New Taipei City Taipei Medical University Shuang Ho Hospital |
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Taiwan | Taipei National Taiwan University Hospital |
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Taiwan | Taipei Taipei Mackay Memorial Hospital |
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Taiwan | Taipei Taipei Veterans General Hospital |
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Taiwan | Taoyuan Linkou Chang Gung Memorial Hospital |
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Spain | Alicante, AC Hosp. Gral. Univ. Dr. Balmis |
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Spain | Barakaldo Hosp. Univ. de Cruces |
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Spain | Barcelona, BA Hosp. de La Santa Creu I Sant Pau |
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Spain | Granada, GD Hosp. Univ. San Cecilio |
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Spain | L'Hospitalet de Llobregat, BA Hosp. Univ. de Bellvitge |
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Spain | Madrid, MD Hosp. Gral. Univ. Gregorio Maranon |
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Spain | Madrid, MD Hosp. Univ. 12 de Octubre |
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Spain | Madrid, MD Hosp. Univ. Infanta Leonor |
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Spain | Madrid, MD Hosp. Univ. de La Paz |
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Spain | Madrid, MD Hosp. Univ. de La Princesa |
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Spain | Madrid, MD Pedro Jaen Group |
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Spain | Valencia, VC Hosp. Univ. I Politecni La Fe |
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South Korea | Busan Pusan National University Hospital |
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South Korea | Gyeonggi-do, 41 Seoul National University Bundang Hospital |
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South Korea | Seoul Hanyang University Medical Center |
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South Korea | Seoul Konkuk University Medical Center |
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South Korea | Seoul Kyung Hee University Hospital |
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South Korea | Seoul Seoul National University Hospital |
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South Korea | Seoul The Catholic University of Korea Seoul St. Mary's Hospital |
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Poland | Bialystok Osteo-Medic s.c A. Racewicz, J Supronik |
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Poland | Bialystok, PL Specderm Poznanska sp j |
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Poland | Elblag Centrum Kliniczno Badawcze J. Brzezicki, B. Gornikiewicz-Brzezicka Lekarze Spolka Partnerska |
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Poland | Krakow Centrum Medyczne Promed |
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Poland | Krakow Lidia Rajzer - Specjalistyczny Gabinet Dermatologiczno-Kosmetyczny |
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Poland | Krakow Specjalistyczny gabinet dermatologiczny Aplikacyjno Badawczy Marek Brzewski Pawel Brzewski Spolka Cywilna |
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Poland | Lodz Centrum Terapii Wspolczesnej J M Jasnorzewska Spolka Komandytowo Akcyjna |
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Poland | Lodz Dermed Centrum Medyczne Sp z o o |
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Poland | Osielsko DermoDent Centrum Medyczne Aldona Czajkowska Rafał Czajkowski s.c. |
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Poland | Poznan Clinical Research Center sp z o o MEDIC R s k |
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Poland | Poznan SOLUMED Centrum Medyczne |
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Poland | Warszawa Klinika Ambroziak Dermatologia |
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Poland | Warszawa Przychodnia Specjalistyczna High Med |
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Poland | Wroclaw Centrum Medyczne Oporow |
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Poland | Wroclaw DERMMEDICA Sp.z o.o. |
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Poland | Wrocław WroMedica I.Bielicka, A.Strzałkowska s.c. |
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Japan | Fukuoka Fukuoka University Hospital |
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Japan | Fukutsu Hino Dermatology Clinic |
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Japan | Gifu Gifu University Hospital |
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Japan | Gunma, 10 Gunma University Hospital |
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Japan | Hokkaido, 01 Asahikawa Medical University Hospital |
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Japan | Hokkaido, 01 JR Sapporo Hospital |
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Japan | Isehara, 14 Tokai University Hospital |
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Japan | Itabashi Ku, 13 Teikyo University Hospital |
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Japan | Kawasaki City, 14 St Marianna University Hospital |
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Japan | Kitakyushu-shi Hospital of the University of Occupational and Environmental Health |
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Japan | Nagoya Nagoya City University Hospital |
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Japan | Nishihara, 47 University of the Ryukyus Hospital |
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Japan | Obihiro-shi, 01 Takagi Dermatology Clinic |
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Japan | Osaka Sayama shi, 27 Kindai University Hospital |
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Japan | Osaka, 27 Public Interest Incorporated Foundation Nipoon Life Saiseikai Nippon Life Hospital |
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Japan | Sakai-shi, 27 Kume Clinic |
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Japan | Sapporo shi, 01 Sapporo Skin Clinic |
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Japan | Sendai, 04 Tohoku University Hospital |
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Japan | Suita-shi, 27 Osaka University Hospital |
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Japan | Tachikawa, 13 Jitaikai Tachikawa dermatology clinic |
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Japan | Takaoka-shi, 16 Shirasaki Dermatology Clinic |
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Japan | Tokyo, 13 Tokyo Medical University Hospital |
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Japan | Tsu Mie University Hospital |
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Hungary | Borgyogyaszati Klinika Pecsi Tudomanyegyetem |
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Hungary | Budapest Obudai Egeszsegugyi Centrum Kft |
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Hungary | Debrecen Debreceni Egyetem Klinikai Kozpont |
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Hungary | Debrecen Derma-B Kft |
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Hungary | Kaposvar Somogy Varmegyei Kaposi Mor Oktato Korhaz |
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Hungary | Szeged SZTE AOK Szent-Gyorgyi Albert Klinikai Kozpont, Borgyogyaszati és Allergologiai Klinika |
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Hungary | Szolnok Allergo-Derm Bakos Kft. |
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Hungary | Veszprem Medmare Egeszsegugyi Es Szolgaltato Bt. |
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Germany | Berlin, BE ISA - Interdisciplinary Study Association GmbH |
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Germany | Bramsche Hautarztpraxis |
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Germany | Dresden Klinische Forschung Dresden GmbH |
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Germany | Dresden Praxis für Dermatologie und Venerologie |
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Germany | Duesseldorf Universitaetsklinikum Duesseldorf |
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Germany | Hamburg, HH MensingDerma research GmbH |
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Germany | Hamburg, HH Universitaetsklinikum Hamburg Eppendorf |
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Germany | Kiel, SH Universitaetsklinikum Schleswig-Holstein Campus Kiel |
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Germany | Langenau, BW Studienzentrum Dr Schwarz Germany |
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Germany | Leipzig Universitatsklinikum Leipzig AOR |
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Germany | Lubeck, SH Universitatsklinikum Schleswig Holstein Campus Lubeck |
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Germany | Mannheim, BW Universitaetsklinikum Mannheim |
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Germany | Munchen Klinik und Poliklinik fur Dermatologie und Allergologie am Biederstein |
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Germany | Potsdam, BB Hautarztpraxis |
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Germany | Rostock, MV Universitaetsmedizin Rostock |
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Canada | Ajax, ON CCA Medical Research Corporation |
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Canada | Barrie, ON SimcoDerm Medical and Surgical Dermatology Centre |
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Canada | Hamilton, ON Dermatrials Research |
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Canada | Richmond Hill, ON York Dermatology Clinic and Research Centre |
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Canada | St. John's, NL Karma Clinical Trials Inc. |
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Canada | Surrey, BC Enverus Medical |
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Canada | Waterloo, ON Alliance Clinical Trials |
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Canada | Windsor, ON XLR8 Medical Research |
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Brazil | Santo Andre, SP Fundacao do ABC - Centro Universitario FMABC |
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Australia | Campbelltown, SA North Eastern Health Specialists |
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Australia | Canberra, ACT Paratus Clinical Research Woden |
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Australia | East Melbourne, VIC Sinclair Dermatology |
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Australia | Melbourne, VIC Skin Health Institute Inc. |
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Australia | Woolloongabba, QLD Veracity Clinical Research |
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Argentina | Buenos Aires, B ARCIS Salud SRL Aprillus asistencia e investigacion |
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Argentina | Buenos Aires, B Instituto Medico De Alta Complejidad (IMAC) |
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Argentina | Caba, B Halitus Instituto Medico S.A. - Dermatologia y Estetica |
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Argentina | Caba, B Hospital Italiano de Buenos Aires |
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Argentina | Caba, B Instituto de Neumonologia y Dermatologia |
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Argentina | La Plata Hospital Italiano de La Plata |
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Argentina | Rosario Instituto Caici Srl. |
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Argentina | San Miguel De Tucuman, T Centro de Investigaciones Medicas Tucuman |
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