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A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Last Updated   May 14, 2025

Want to learn how to participate in this trial?

81201887MDG3002

OVERVIEW

  • Sexes Eligible for Study
    all
  • Age
    60+ years
  • Phase
    phase 2
  • Sites
    47 Sites
  • Status
    Recruiting

SUMMARY

The purpose of this study is to assess the long-term safety and tolerability after an intravitreal injection (a shot of medicine into the eye) of JNJ-81201887 administered in parent clinical studies.

CONDITIONS

  • Geographic Atrophy
  • Macular Degeneration

ELIGIBILITY


Inclusion Criteria:

* Participants who were enrolled and received treatment with JNJ-81201887 or sham in a parent clinical study (81201887MDG2001, 81201887MDG1003)
* Females (women of childbearing potential), male participants, and partners of male participants will not be required to use contraception in this LTE study
* Must sign an informed consent form (ICF) indicating that participant understands the purpose of, and procedures required for, the study and is willing to participate in the study. The ICF may be signed by an impartial witness and/or legally designated representative depending on national/local regulations


Exclusion Criteria:

* There are no exclusion criteria for this LTE study


Inclusion Criteria:

* Participants who were enrolled and received treatment with JNJ-81201887 or sham in a parent clinical study (81201887MDG2001, 81201887MDG1003)
* Females (women of childbearing potential), male participants, and partners of male participants will not be requir

More...

DETAILS

LOCATIONS

Locations in:
United States, Spain, China, Germany, Italy, Netherlands, Poland, Türkiye
Country (8) City or Province (47) Status
United States Tucson Retina Associates Southwest PC
RECRUITING
United States Fullerton Retina Consultants of Orange County
RECRUITING
United States Walnut Creek Bay Area Retina Associates
RECRUITING
United States Gainesville VitreoRetinal Associates, PA
RECRUITING
United States Pensacola Retina Specialty Institute
RECRUITING
United States Marietta Marietta Eye Clinic
RECRUITING
United States Portland Maine Eye Center
RECRUITING
United States Hagerstown Cumberland Valley Retina Consultants
RECRUITING
United States Grand Rapids Foundation for Vision Research
RECRUITING
United States Saint Louis The Retina Institute
RECRUITING
United States Asheville Asheville Eye Associates - Western Carolina Retinal Associates
RECRUITING
United States Hickory Graystone Eye
RECRUITING
United States Cincinnati Cincinnati Eye Institute
RECRUITING
United States Erie Erie Retina Research
RECRUITING
United States Willow Park Strategic Clinical Research Group
RECRUITING
United States Lynchburg Piedmont Eye Center
RECRUITING
United States Norfolk Wagner Kapoor Research institute
RECRUITING
United States Spokane Spokane Eye Clinical Research
RECRUITING
United States Poway Retina Consultants San Diego
RECRUITING
United States Saint Louis Park Retina Consultants of Minnesota
RECRUITING
United States Reno Sierra Eye Associates
RECRUITING
United States Liverpool Retina-Vitreous Surgeons of Central New York
RECRUITING
United States Wake Forest NC Retina Associates
RECRUITING
United States Beaufort Charleston Neuroscience Institute, LLC
RECRUITING
United States Bellaire Retina and Vitreous of Texas, PLLC
RECRUITING
United States Dallas Texas Retina Associates
RECRUITING
Spain Burjassot Clinica Oftalvist Valencia
RECRUITING
United States La Jolla Shiley Eye Institute Jacobs Retina Center
RECRUITING
United States Fort Lauderdale Retina Group of Florida
RECRUITING
United States Saint Petersburg Retina Vitreous Associates of Florida
RECRUITING
United States Baltimore Retina Specialists
RECRUITING
United States Chevy Chase The Retina Group of Washington
RECRUITING
United States Durham Duke Eye Center
RECRUITING
United States The Woodlands Retina Consultants of Texas
RECRUITING
China Shanghai Shanghai General Hospital
RECRUITING
Germany Hannover Medizinische Hochschule Hannover
RECRUITING
Germany Muenster Augenzentrum am St Franziskus Hospital Munster
RECRUITING
Italy Milano Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico
RECRUITING
Netherlands Nijmegen Radboudumc
RECRUITING
Poland Bydgoszcz Oftalmika
RECRUITING
Spain Barcelona Centro de Oftalmologia Barraquer
RECRUITING
Spain Barcelona Centro Medico Teknon S.L.
RECRUITING
Spain Madrid Hosp. Univ. 12 de Octubre
RECRUITING
Spain Madrid Clinica Baviera Madrid Castellana
RECRUITING
Spain Pamplona Clinica Univ. de Navarra
RECRUITING
Spain Sant Cugat del Valles Idc Salud Hosp. Gral. de Catalunya
RECRUITING
Türkiye Ankara Baskent University Ankara Hospital
RECRUITING
Show More
Geo Locations

32.22174, -110.92648

33.87029, -117.92534

37.90631, -122.06496

29.65163, -82.32483

30.42131, -87.21691

33.9526, -84.54993

43.66147, -70.25533

39.64176, -77.71999

42.96336, -85.66809

38.62727, -90.19789

35.60095, -82.55402

35.73319, -81.3412

39.12713, -84.51435

42.12922, -80.08506

32.76263, -97.65058

37.41375, -79.14225

36.84681, -76.28522

47.65966, -117.42908

32.96282, -117.03586

44.9483, -93.34801

39.52963, -119.8138

43.10646, -76.2177

35.97987, -78.50972

32.43158, -80.66983

29.70579, -95.45883

32.78306, -96.80667

39.50984, -0.41327

32.84727, -117.2742

26.12231, -80.14338

27.77086, -82.67927

39.29038, -76.61219

39.00287, -77.07115

35.99403, -78.89862

30.15799, -95.48938

31.22222, 121.45806

52.37052, 9.73322

51.96236, 7.62571

45.46427, 9.18951

51.8425, 5.85278

53.1235, 18.00762

41.38879, 2.15899

41.38879, 2.15899

40.4165, -3.70256

40.4165, -3.70256

42.81687, -1.64323

41.47063, 2.08611

39.91987, 32.85427

x
50

Indicates 50+ sites in this region: click to zoom in.

10

Indicates 10+ sites in this region: click to zoom in.

5

Indicates < 10 sites in this region: click to zoom in.

Corresponds to individual site.

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