A Study of the Efficacy and Safety of Guselkumab in Participants with Moderately to Severely Active Crohn's Disease

Last Updated   August 10, 2019 - 00:00

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OVERVIEW

  • Gender
    all
  • Age
    18+ years
  • Phase
    phase 3
    The drug or treatment is given to large groups of people to confirm its effectiveness, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
  • Sites
    470 sites
  • Status
    Recruiting

SUMMARY

The purpose of this program is to evaluate the efficacy and safety of guselkumab in participants with Crohn’s disease.

CONDITIONS

  • Crohn Disease

ELIGIBILITY

Inclusion Criteria:

  • • Have Crohn’s disease (CD) or fistulizing Crohn’s disease of at least 3 months duration (defined as a minimum of 12 weeks), with colitis, ileitis, or ileocolitis, confirmed at any time in the past by radiography, histology, and/or endoscopy
  • • Have moderate to severe CD as assessed by CDAI, stool frequency (SF), and abdominal pain (AP) scores, and Simple Endoscopic Score for Crohn's Disease (SES-CD)
  • • Have screening laboratory test results within the protocol specified parameters
  • • A female participant of childbearing potential must have a negative urine pregnancy test result at screening and baseline
  • • Demonstrated intolerance or inadequate response to conventional or to biologic therapy for CDExclusion Criteria:
  • • Current diagnosis of ulcerative colitis or indeterminate colitis
  • • Has complications of Crohn’s disease, such as symptomatic strictures or stenoses, short gut syndrome, or any other manifestation
  • • Unstable doses of concomitant Crohn's disease therapy
  • • Receipt of Crohn’s disease approved biologic agents, investigational agents, or procedures outside of permitted timeframe as specified in the protocol
  • • Prior exposure to p40 inhibitors or p19 inhibitors
  • • Any medical contraindications preventing study participation

DETAILS

This program consists of 3 separate studies: a 48-week Phase 2 dose-ranging study (GALAXI 1) and two 48-week Phase 3 confirmatory studies (GALAXI 2 and GALAXI 3). In Phase 2, safety and efficacy of guselkumab dose regimens will be evaluated to support the selection of induction and maintenance dose regimens for confirmatory evaluation in Phase 3. Participants who complete the 48-week Phase 2 or Phase 3 studies may be eligible to enter the long term extension (LTE). Throughout the 3 studies, efficacy, pharmacokinetic, biomarkers, and safety will be assessed.

LOCATIONS

Locations in:
Germany, France, Croatia, China, Brazil, Turkey, Spain, Lebanon, Italy, Australia, Austria, Belgium, Canada, Switzerland, Colombia, Greece, Hungary, India, Israel, Jordan, Latvia, New Zealand, Poland, Portugal, Tunisia, Japan, Lithuania, Slovakia, Ukraine, Georgia, Serbia, Belarus, Netherlands, Puerto Rico, Saudi Arabia, South Korea, Czechia, Bosnia and Herzegovina, Russia, Chile, United Kingdom, Taiwan, United States, Malaysia, North Macedonia
City or Province (470) Country (45) Status
Bonn Universitatsklinikum Bonn Germany
Withdrawn
Clermont-Ferrand Cedex 3 CHU Clermont-Ferrant-Hopital Hotel Dieu France
Withdrawn
Osijek, 14 Klinički bolnički centar Osijek Croatia
Not yet recruiting
Guangzhou, 44 Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University China
Not yet recruiting
Brasília, DF L2IP - Instituto de Pesquisas Clínicas Brazil
Not yet recruiting
Joaaba Hospital Universitrio Santa Terezinha Brazil
Not yet recruiting
Porto Alegre, RS Hospital Ernesto Dornelles Brazil
Withdrawn
Curitiba Hospital Nossa Senhora Das Gracas Brazil
Not yet recruiting
Porto Alegre Hospital de Clínicas de Porto Alegre/ HCPA / UFRGS Brazil
Not yet recruiting
İstanbul, IST Bezmialem University Medical Faculty Turkey
Withdrawn
Ferrol COMPLEJO HOSP UNIV. DE FERROL Spain
Not yet recruiting
Majadahonda, MD HOSP. UNIV. PTA. DE HIERRO MAJADAHONDA Spain
Withdrawn
Fuenlabrada, MD HOSP. UNIV. FUENLABRADA Spain
Withdrawn
Beirut, BA St Georges Hospital university medical centre Lebanon
Withdrawn
Saida Hammoud Hospital Lebanon
Withdrawn
Bologna Policlinico S.Orsola Malpighi, AOU di Bologna Italy
Not yet recruiting
Roma IBD Unit- Sandro Pertini Hospital Italy
Not yet recruiting
Herston, QLD Royal Brisbane and Women's Hospital Australia
Withdrawn
Wien Akh Wien Austria
Not yet recruiting
Antwerpen GZA Ziekenhuizen Belgium
Withdrawn
São Paulo, SP Hospital Israelita Albert Einstein Brazil
Withdrawn
Sao Paulo, SP Hemomed Brazil
Not yet recruiting
Botucatu, SP Universidade Estadual Paulista 'Julio De Mesquita Filho' Brazil
Not yet recruiting
Santo Andre, SP Pesquisare Saude Brazil
Not yet recruiting
Santo André, SP CEMEC – Centro Multidisciplinar de Estudos Clínicos Brazil
Not yet recruiting
Goiania Instituto Goiano de Gastroenterologia e Endoscopia Digestiva Brazil
Not yet recruiting
Blumenau, SC MK Blumenau Pesquisa Clínica Brazil
Not yet recruiting
Vaughan, ON Toronto Digestive Disease Associates Inc Canada
Withdrawn
Bern, BE Gastroenterologische Praxis Balsiger und Seibold Switzerland
Withdrawn
Chongqing, 97 The Second Affiliated Hospital of Chongqing Medical University China
Not yet recruiting
Beijing, 11 Beijing Friendship Hospital China
Not yet recruiting
Chengdu, 51 West China Hospital, Sichuan University China
Not yet recruiting
Wuhan, 42 Wuhan Union Hospital China
Not yet recruiting
Changsha, 43 The second Xiangya Hospital of Central South University China
Not yet recruiting
Beijing, 11 Peking University First Hospital China
Not yet recruiting
Shanghai, 31 Shanghai East Hospital China
Not yet recruiting
Beijing, 11 The Military General Hospital of Beijing PLA China
Not yet recruiting
Shanghai, 31 Shanghai General Hospital China
Not yet recruiting
Bogota Endocare Ltda. Colombia
Not yet recruiting
Halle Martin-Luther-Universitaet Halle-Wittenberg - Universitaetsk Germany
Withdrawn
Berlin, BE Vivantes Klinikum Spandau Germany
Withdrawn
Madrid, MD HOSP. CLINICO SAN CARLOS Spain
Not yet recruiting
Caen Centre Hospitalier Universitaire (CHU) de Caen France
Withdrawn
Ioannina University General Hospital of Ioannina Greece
Withdrawn
Gyula Békés Megyei Központi Kórház Pándy Kálmán Tagkórház Hungary
Withdrawn
Surat, GJ Surat Institute of Digestive Sciences Hospitals India
Not yet recruiting
Jaipur, RJ SMS Hospital India
Not yet recruiting
New Delhi, DL All India Institute of Medical Sciences India
Not yet recruiting
Varanasi, UP Samvedana Hospital India
Not yet recruiting
Vijayawada, AP Andhra Hospitals India
Not yet recruiting
Bangalore, KA Bangalore Medical College and Research Institute India
Withdrawn
Ahmedabad, GJ Kaizen Hospital India
Withdrawn
Nashik, MH Chopda Medicare & Research Centre Pvt.Ltd, Magnum Heart Institute India
Not yet recruiting
Ludhiana, PB Baba Farid University of Health Sciences - Christian Medical India
Not yet recruiting
Surat, GJ Nirmal Hospital Pvt. Ltd. India
Not yet recruiting
Vijayawada, AP Government Siddhartha Medical College India
Not yet recruiting
Tel Aviv Tel Aviv Sourasky Medical Center Israel
Withdrawn
Jerusalem Hadassah Medical Organization Ein Kerem Israel
Withdrawn
Hadera Hillel Yaffe Medical Center Israel
Withdrawn
Torino Ospedale Molinette, AO Città della Salute e della Scienza di Italy
Withdrawn
Milano Gruppo Ospedaliero San Donato - Istituto di Ricovero e Cura Italy
Not yet recruiting
Firenze AOU Careggi Italy
Not yet recruiting
Torino S.C. Gastroenterologia Italy
Not yet recruiting
Udine Azienda Ospedaliero Universitaria S.Maria Della Misericordia Italy
Not yet recruiting
Cento Ospedale Santissima Annunziata Italy
Not yet recruiting
Rome Complesso Integrato Columbus Italy
Not yet recruiting
Amman Prince Hamza Hospital Jordan
Withdrawn
Jbeil Notre Dame De Secours Lebanon
Withdrawn
Beirut, BA Bellevue Medical Center Lebanon
Not yet recruiting
Riga Riga East Clinical University Hospital Latvia
Not yet recruiting
Auckland, AUK Auckland City Hospital New Zealand
Not yet recruiting
Dunedin, OTA Dunedin Hospital New Zealand
Not yet recruiting
Warszawa Centrum Medyczne Pratia Warszawa Poland
Withdrawn
Krakow Centrum Medyczne Pratia Krakow Poland
Withdrawn
Lisbon Centro Hospitalar Lisboa Norte EPE - Hospital Pulido Valente Portugal
Not yet recruiting
Tunis, TU Military Hospital of Instruction of Tunis Tunisia
Not yet recruiting
Sousse, SO Hopital Universitaire Sahloul Tunisia
Not yet recruiting
Nabul, NA Hopital Regional Mohamed Tahar El Maamouri Tunisia
Not yet recruiting
Tunis, TU Hopital Habib Thameur Tunisia
Not yet recruiting
Gaziantep, GAZ Gaziantep University School of Medicine Turkey
Withdrawn
Helifax, NS QEII Health Sciences Centre Canada
Withdrawn
Edmonton, AB GI Research Institute (G.I.R.I.) Canada
Withdrawn
Shanghai, 31 Shanghai Renji Hospital China
Not yet recruiting
Nanjing, 32 Zhongda Hospital,Southeast University China
Not yet recruiting
Guangzhou, 44 Chongqing Qijiang People Hospital China
Not yet recruiting
Shanghai, 31 Ruijin Hospital, Shanghai Jiao Tong University China
Not yet recruiting
Huelva, HL HOSP. GRAL. JUAN RAMON JIMENEZ Spain
Suspended
Tomishiro Yuaikai Tomishiro Central Hospital Japan
Withdrawn
Shanghai, 31 Tongji Hospital of Tongji University China
Not yet recruiting
Hangzhou, 33 The Second Affiliated Hospital of Zhejiang University China
Not yet recruiting
Kadikoy, IST Istanbul Medeniyet University Goztepe Training and Research Hospital Turkey
Not yet recruiting
Hangzhou, 33 Sir Run Run Shaw Hospital, Zhejiang University China
Not yet recruiting
Shanghai, 31 Second Military Medical University (SMMU) China
Not yet recruiting
Niigata Niigata University Medical & Dental Hospital Japan
Withdrawn
Edmonton, AB University of Alberta- Ziedler Ledcor Centre Canada
Not yet recruiting
London, ON London Health Sciences Centre Canada
Not yet recruiting
Guangzhou, 44 Sun Yat-sen University - The Sixth Affiliated Hospital Guangdong Gastrointestinal Hospital China
Not yet recruiting
Nanchang, 36 The First Affiliated Hospital of NanChang University China
Not yet recruiting
Tunis Jebbari, TU Hospital La Rabta Tunisia
Not yet recruiting
Clichy-Sous-Bois Hopitaux Universitaires Paris Nord Val de Seine - Hopital Beaujon France
Withdrawn
Nahariya Galilee Medical Center Israel
Withdrawn
Medellin, ANT HOSPITAL PABLO TOBÓN URIBE Colombia
Withdrawn
Mosonmagyarovár Karolina Hospital Hungary
Suspended
Budapest Obudai Egeszsegugyi Centrum Kft. Hungary
Suspended
Budapest Semmelweis Egyetem Hungary
Suspended
Békéscsaba Réthy Pál Kórház - Rendelőintézet Hungary
Suspended
Budapest Meddica Centre Hungarian Defence Froces Hungary
Suspended
Szeged Szegedi Tud.Egyetem Szent-Gyorgyi Albert Klin. Közp. Hungary
Suspended
Budapest Szent János Kórház és Észak-budai Egyesített Kórházak Hungary
Suspended
Kaposvár KAPOSI MÓR OKTATÓ KÓRHÁZ, KARDIOLÓGIAI RÉSZLEG Hungary
Suspended
Chandigarh, CH Postgraduate Institute of Medical Education and Research India
Not yet recruiting
Mumbai, MH P.D. Hinduja National Hospital and - Medical Research Center India
Not yet recruiting
Nanjing, 32 Nanjing Drum Tower Hospital China
Not yet recruiting
Amman Jordan University Hospital Jordan
Not yet recruiting
Tournai, WHT CHwapi Belgium
Recruiting
Bruxelles, BRU CHU Saint-Pierre Belgium
Recruiting
Osaka Kinshu-kai Infusion Clinic Japan
Recruiting
Mitaka Kyorin University Hospital Japan
Suspended
Asahikawa Asahikawa City Hospital Japan
Recruiting
Okinawa Keiaikai Chibana Clinic Japan
Recruiting
Zamosc ETG Zamosc Poland
Recruiting
Zhangzhou, 35 Zhangzhou Municipal Hospital of Fujian Province China
Not yet recruiting
Zagreb University Hospital Dubrava Croatia
Recruiting
Kaunas Lietuvos sveikatos mokslų universiteto ligoninė Kauno klinik Lithuania
Recruiting
Parkville, VIC Royal Melbourne Hospital Australia
Recruiting
Berlin, BE Krankenhaus Waldfriede Mitte Germany
Recruiting
Berlin-Karlshorst, BE Gastroenterologische Spezialpraxis - Berlin-Karlshorst Germany
Recruiting
Hamburg, HH Asklepios Westklinikum Germany
Recruiting
Lille CHRU de Lille - Hôpital Claude Huriez France
Recruiting
Takamatsu Kagawa Prefectural Central Hospital Japan
Recruiting
Osaka Osaka City University Hospital Japan
Recruiting
Kofu Yamanashi Prefectural Central Hospital Japan
Recruiting
Oita Oita Red Cross Hospital Japan
Recruiting
Sapporo, 01 Sapporo East tokusyu-kai Hospital Japan
Recruiting
Hirosaki Hirosaki National Hospital Japan
Recruiting
Kyoto Kyoto Prefectural University of Medicine Hospital Japan
Recruiting
Vilnius Vilniaus Universiteto Ligonines Santariskiu Klinikos Lithuania
Recruiting
Warszawa Wojskowy Instytut Medyczny Poland
Recruiting
Krakow Centrum Medyczne Promed Poland
Recruiting
Wroclaw ARS MEDICA Rybak Maria, Rybak Zbigniew, s.c. Poland
Recruiting
Sopot, PM Endoskopia Sp z o.o. Poland
Recruiting
Lublin Gastromed Spotka Z Ograniczona Odpowiedzialnoscia Sp. K. Poland
Recruiting
Warszawa Centrum Badawcze Wspolczesnej Terapii Poland
Recruiting
Warsaw NZOZ Vivamed Zespol Lekarzy Specjalistow Poland
Recruiting
Rzeszow Centrum Medyczne 'Medyk' Sp. z o.o. K. Poland
Recruiting
Wroclaw Przychodnia Vistamed Poland
Recruiting
Presov GASTRO I. s.r.o. Slovakia
Recruiting
Kosice ENDOMED s.r.o Slovakia
Recruiting
Sumy Sumska oblasna klinichna likarnia Ukraine
Withdrawn
Hefei, 34 The 1st affiliated hospital of Anhui Medical University China
Not yet recruiting
Münster, NW Gemeinschaftspraxis Germania-Campus Germany
Recruiting
Kagoshima Sameshima Hospital Japan
Recruiting
Morioka Iwate Medical University Hospital Japan
Recruiting
Wierzchoslawice Centrum Zdrowia Tuchow Poland
Recruiting
Krakow Centrum medyczne plejady Poland
Recruiting
Hyderabad Asian Institute Of Gastroenterology India
Not yet recruiting
Shenzhen, 44 University of Hong Kong-Shenzhen Hospital China
Not yet recruiting
Beijing, 11 Peking University Third Hospital China
Not yet recruiting
Sakura Toho University Sakura Medical Center Japan
Recruiting
Heraklion University Hospital of Heraklion Greece
Recruiting
Tbilisi, TB TSMU The First University Clinic Georgia
Recruiting
Prahran, VIC The Alfred Hospital Australia
Recruiting
Banska Bystrica FNsP F.D.R. Banska Bystrica Slovakia
Recruiting
Montreal, QC MUHC Center for Applied Ethics Canada
Recruiting
Winnipeg, MB Health Sciences Centre Canada
Recruiting
Telavi, KA LTD Unimed Kakheti- Telavi Referral Hospital Georgia
Recruiting
Tbilisi, TB Israel Georgian medical research clinic Helsicore Georgia
Recruiting
Kochi Kochi National Hospital Japan
Recruiting
Kobe Aoyama Naika Clinic Japan
Recruiting
Belgrade Clinical Hospital Center Bezanijska Kosa Serbia
Recruiting
Belgrade Zvezdara University Medical Center Serbia
Recruiting
Kragujevac Clinical Center Kragujevac Serbia
Recruiting
Chikushino Fukuoka University Chikushi Hospital Japan
Recruiting
Sapporo, 01 Sapporo-Kosei General Hospital Japan
Recruiting
Belgrade Clinical Center of Serbia Serbia
Recruiting
Belgrade Special hospital for Internal diseases, Oncomed system Serbia
Recruiting
Reims, Cedex Hôpital Robert Debré France
Recruiting
Montpellier Cedex 5 CHRU Montpellier - Hopital Saint-Eloi France
Recruiting
Madrid, MD HOSP. UNIV. RAMON Y CAJAL Spain
Withdrawn
Vigo, PO HOSP. ALVARO CUNQUEIRO Spain
Recruiting
South Brisbane, QLD Mater Hospital Brisbane Australia
Recruiting
Woolloongabba, QLD Princess Alexandra Hospital Australia
Recruiting
Frankfurt/Main, HE Agaplesion Frankfurter Diakonie Kliniken GmbH, Markus Krankenhaus Germany
Recruiting
Hannover, NI Medizinische Hochschule Hannover Germany
Recruiting
Regensburg Praxiszentrum Alte Mälzerei Germany
Recruiting
Paris HÔPITAL SAINT LOUIS France
Withdrawn
Paris Groupement Hospitalier Universitaire Ouest France
Recruiting
Saint Etienne CHU Saint-etienne France
Recruiting
Toulouse CHU Rangueil France
Recruiting
Tbilisi, TB LTD 'Georgia Archangel St. Michael Multiprofile Clinical Hospital' Georgia
Recruiting
Athens LAIKO GENERAL HOSPITAL OF ATHENS Greece
Recruiting
Zadar Opca bolnica Zadar Croatia
Recruiting
Rozzano Istituto Clinico Humanitas Rozzano, IRCCS Italy
Recruiting
Tsu Mie University Hospital Japan
Recruiting
Nagoya Nagoya City University Hospital Japan
Recruiting
Izumo Shimane University Hospital Japan
Recruiting
Olsztyn Wojewodzki Szpital Specjalistyczny w Olsztynie Poland
Recruiting
Tychy H-T Centrum Medyczne Endoterapia Poland
Recruiting
Szczecin Twoja Przychodnia - Szczecinskie Centrum Medyczne Poland
Recruiting
Uzhgorod Transcarpathian Regional Clinical Hospital Ukraine
Recruiting
Vinnytsia Medical Clinical Investigational Center of Medical Center 'Health Clinic' Ukraine
Recruiting
Zaporozhye KU 6 miska klinichna likarnia ZMR Ukraine
Recruiting
Penrith, NSW Nepean Hospital Australia
Recruiting
Hamburg, HH Martini-Klinik am Universitätsklinikum Hamburg-Eppendorf Urologie Germany
Recruiting
Gifu Gifu University Hospital Japan
Recruiting
Toruń Toruńskie Centrum Gastrologiczne Poland
Recruiting
Ankara, ANK Ankara University Medical Faculty Turkey
Suspended
Malatya, MAL Inonu Universitesi Turgut Ozal Tip Merkezi, Ic Hastaliklari Turkey
Suspended
Kortrijk Az Groeninge Belgium
Recruiting
Nantes CHU de Nantes hôtel-Dieu France
Recruiting
Toulouse Hopital Purpan France
Recruiting
Ramat Gan Chaim Sheba Medical Center Israel
Recruiting
Gomel Gomel Regional Clinical Hospital Belarus
Recruiting
Minsk BelMAPE Belarus
Withdrawn
Gomel Republican Research Centre of Radiation Medicine and Human E Belarus
Recruiting
Heidelberg, VIC Austin Hospital Australia
Recruiting
Izmir Dokuz Eylul Universitesi Tip Fakultesi Turkey
Recruiting
D:14/4 Nisantasi Acibadem Fulya Hospital Turkey
Recruiting
Salzburg, SAL Universitätsklinikum Salzburg - Landeskrankenhaus Austria
Recruiting
Berlin, BE Universitaetsklinikum Charite, Campus Virchow Klinikum Germany
Recruiting
Berlin, BE Charité - Campus Mitte Germany
Recruiting
Colombes Cedex Hopital Louis Mourier France
Not yet recruiting
Besançon Hôpital Besançon France
Recruiting
Pierre-Bénite CENTRE HOSPITALIER LYON SUD France
Recruiting
Amiens CHU Amiens France
Recruiting
Marseille Aphm - Hopital Nord France
Recruiting
Zagreb CH Sestre Milosrdnice Croatia
Recruiting
Zerifin Assaf Harofeh Medical Center Israel
Recruiting
Petah Tikva Rabin Med Ctr Beilinson Hosp Israel
Recruiting
Afula Ha'Emek Medical Center Israel
Recruiting
Jerusalem Shaare Zedek Medical Center Israel
Recruiting
Nagasaki Nagasaki University Hospital Japan
Recruiting
Wakayama Wakayama Medical University Hospital Japan
Recruiting
Otsu Shiga University of Medical Science Hospital Japan
Recruiting
Kurume Kurume University Hospital Japan
Recruiting
Toyoake Fujita Health University Hospital Japan
Recruiting
Riga Pauls Stradins Clinical University Hospital Latvia
Recruiting
Ankara, ANK Hacettepe University Medical Faculty Turkey
Recruiting
Kocaeli, KOC Kocaeli University Medical Faculty Turkey
Recruiting
Kharkiv Kharkiv City Clinical Hospital Ukraine
Recruiting
Kyiv O.O.Bogomolets National Medical University, Kyiv City Clinical Hospital #18, Ukraine
Recruiting
Clayton, VIC Monash Health, Monash Medical Centre Australia
Recruiting
Nedlands, WA Sir Charles Gairdner Hospital Australia
Recruiting
Calgary, AB University of Calgary Canada
Recruiting
Elazig Firat University Hospital Turkey
Recruiting
Hatay, HTY Mustafa Kemal University Research and Practise Hospital Turkey
Recruiting
Osaka Osaka University Hospital Japan
Recruiting
Zaporizhzhia Zaporizka oblasna klinichna likarnia Ukraine
Suspended
Kobe Kobe University Hospital Japan
Recruiting
Suzhou, 32 The first affiliated hospital of suzhou University China
Not yet recruiting
Beijing, 11 Peking University People's Hospital China
Not yet recruiting
Amsterdam Academisch Medisch Centrum Universiteit van Amsterdam Netherlands
Not yet recruiting
Concord, NSW Concord Hospital Australia
Not yet recruiting
Sao Paulo, SP CEP - Hospital das Clinicas da FMUSP Brazil
Not yet recruiting
Kfar Saba Meir Medical Center Israel
Recruiting
Frankfurt JWG-University Hospital Germany
Recruiting
Vitebsk Vitebsk Regional Clinical Hospital Belarus
Recruiting
Grodno Grodno Regional Clinical Hospital Belarus
Recruiting
Ternopil Ternopil municipal hospital #1 Ukraine
Recruiting
North Terrace, SA Royal Adelaide Hospital Australia
Recruiting
Oviedo, AS HOSP. UNIV. CENTRAL DE ASTURIAS Spain
Recruiting
Zagreb University Hospital Center Zagreb Croatia
Recruiting
Ashkelon Barzilai Medical Center Israel
Recruiting
Irbid King Abdullah University Hospital Jordan
Recruiting
Hiroshima Hiroshima University Hospital Japan
Recruiting
Adana, ADA Cukurova University Medical Faculty Balcali Hospital Turkey
Withdrawn
Mersin Mersin University Medical Faculty Turkey
Withdrawn
Tbilisi, TB Institute of Clinical Cardiology, Ltd. Georgia
Recruiting
Ponce Hopital San Cristobal Puerto Rico
Not yet recruiting
Riyadh King Abdul Aziz Medical City for National Guard Health Affairs Saudi Arabia
Not yet recruiting
Riyadh King Khalid Hospital Saudi Arabia
Withdrawn
Makkah King Abdullah Medical City in Holy Capital Saudi Arabia
Not yet recruiting
Riga Alda Pukisa arsta prakse Latvia
Not yet recruiting
Seoul Samsung Medical Center South Korea
Recruiting
Daegu Kyungpook National University Hospital South Korea
Recruiting
Praha 7 ISCARE I.V.F. a.s. Czechia
Recruiting
Hradec Kralove Hepato-gastroenterologie HK, s.r.o. Czechia
Recruiting
Praha 10 Fakultni nemocnice Kralovske Vinohrady Czechia
Recruiting
Ostrava - Poruba Fakultni nemocnice Ostrava Czechia
Withdrawn
Rio de Janeiro, RJ UFRJ-Hospital Universitário Clementino Fraga Filho Brazil
Not yet recruiting
Mostar Clinical hospital Mostar Bosnia and Herzegovina
Recruiting
Banja Luka University Clinical Centre of the Republic of Srpska Bosnia and Herzegovina
Recruiting
Girona, GI HOSP. UNIV. DR. JOSEP TRUETA Spain
Recruiting
Omsk Clinical Diagnostic Center 'Ultramed' Russia
Recruiting
Modena AOU Policlinico di Modena Italy
Withdrawn
Zenica Kantonalna bolnica Zenica Bosnia and Herzegovina
Recruiting
Sao Jose do Rio Preto Fundacao Faculdade Regional De Medicina De Sao Jose Do Rio Preto Brazil
Not yet recruiting
Viña del Mar Instituto Oncologico Viña del Mar Chile
Withdrawn
Hradec Kralove FN Hradec Kralove Czechia
Withdrawn
Horovice NH Hospital, a.s. Czechia
Recruiting
Torrejón de Ardoz, MD HOSP. UNIV. DE TORREJON Spain
Recruiting
Strasbourg CEDEX Hôpitaux Universitaires de Strasbourg - Hôpital de Hautepierre France
Recruiting
Nice cedex 03 CHU de Nice Hopital de l Archet France
Recruiting
Chambray les tours Centre CHRU de Tours - Hopital Trousseau France
Not yet recruiting
London Whipps Cross University Hospital United Kingdom
Withdrawn
Barnsley, SYK Barnsley District General Hospital United Kingdom
Not yet recruiting
Nottingham, NTT Nottingham University Hospitals NHS Trust United Kingdom
Withdrawn
Cambridge, CAM Addenbrooke's Hospital United Kingdom
Not yet recruiting
Haifa, H Bnai Zion Medical Center Israel
Recruiting
Bunkyo-ku, 13 Juntendo University Hospital Japan
Recruiting
Hamamatsu-shi Matsuda Hospital Japan
Recruiting
Otsu-shi National Hospital Organization Higashi Ohmi General Medical Center Japan
Recruiting
Seongnam, 41 CHA Bundang Medical center, CHA University South Korea
Recruiting
Seoul Kyung Hee University Medical Center South Korea
Withdrawn
Seoul Yonsei University College of Medicine South Korea
Recruiting
Seoul Kangbuk Samsung Hospital South Korea
Recruiting
YangCheon-Gu Ewha Womans University Mokdong Hospital South Korea
Recruiting
Suwon-si, 41 The Catholic University of Korea St. Vincent's Hospital South Korea
Recruiting
Busan Dong-A University Hospital South Korea
Recruiting
Busan Inje University Haeundae Paik Hospital South Korea
Recruiting
Seoul Chung-Ang University Hospital South Korea
Recruiting
Ansan-si, 41 Korea University Ansan Hospital South Korea
Recruiting
Sittard-Geleen, LI Stichting Zuyderland Medisch Centrum Netherlands
Recruiting
Wroclaw Melita Medical Sp. z o.o. Poland
Recruiting
Kazan Kazan State Medical University Russia
Recruiting
Samara NUZ 'Railway Clinical Hospital on Samara station of LLC 'Russian Railways' Russia
Recruiting
Saint-Petersburg City Hospital named after St. Martyr Elizabeth Russia
Recruiting
Moscow State Scientific Centre of Coloproctology Russia
Withdrawn
St. Petersburg LLC PoliClinic EXPERT Russia
Withdrawn
Saint-Petersburg City Clinical Hospital # 26 Russia
Recruiting
Rostov-on-Don City Hospital #20 Russia
Recruiting
Novosibirsk Federal State Budgetary Institution 'Scientific Research In Russia
Withdrawn
Saint Petersburg City Hospital #9 Russia
Withdrawn
Samara Medical University Reaviz Russia
Recruiting
Saint Petersburg Clinical Hospital #122 n.a. after L.G. Sokolov Russia
Recruiting
Rostov-na-Donu GBOU VPO Rostov State Medical University Russia
Recruiting
Krasnoyarsk KGBUZ 'Regional Clinical Hospital' Russia
Recruiting
Novosibirsk Novosibirsk Region Clinical Hospital Russia
Withdrawn
St Petersburg St.Petersburg State Medical University n.a.Pavlov Russia
Recruiting
St. Petersburg City Clinical Hospital #31 Russia
Recruiting
Taipei National Taiwan University Hospital Taiwan
Recruiting
Changhua Chang-Hua Christian Hospital Taiwan
Recruiting
Taoyuan Chang-Gung Memorial Hospital-Linkou Taiwan
Not yet recruiting
Taichung China Medical University Hospital Taiwan
Recruiting
Kherson KZ Khersonska Miska Klinichna Likarnia Im. Ye.Ie.Karabelesha Ukraine
Recruiting
Odesa Odeska oblasna klinichna likarnia Ukraine
Recruiting
Kyiv Kyiv Regional Clinical Hospital Ukraine
Recruiting
Inverness, FL Elite Research Network - Nature Coast Clinical Research, LLC United States
Recruiting
Rialto, CA Inland Empire Liver Foundation United States
Recruiting
Lancaster, CA Om Research LLC United States
Recruiting
Chesterfield, MI Clinical Research Institute of Michigan, LLC United States
Recruiting
Chesapeake, VA Gastroenterology Associates of Tidewater United States
Recruiting
New York, NY NYU Langone Medical Center United States
Recruiting
Chapel Hill, NC University North Carolina at Chapel Hill United States
Recruiting
Atlanta, GA ATLANTA GASTROENTEROLOGY ASSOCIATES United States
Recruiting
Charlottesville, VA University of Virginia United States
Withdrawn
Southlake, TX Texas Digestive Disease Consultants United States
Recruiting
Marietta, GA Gastrointestinal Specialists of Georgia United States
Withdrawn
Hialeah, FL Harmony Medical Research Institute, Inc. United States
Recruiting
Orlando, FL Florida Hospital United States
Recruiting
San Antonio, TX Gastroenterology Research of America, LLC United States
Recruiting
Anaheim, CA Advanced Research Center Inc United States
Recruiting
kissimmee, FL SIH Research United States
Recruiting
Boston, MA Harvard Medical School-Beth Israel Deaconess Medical Center United States
Not yet recruiting
Nashville, TN Vanderbilt University Medical Center United States
Recruiting
Baton Rouge, LA Gastroenterology Associates United States
Recruiting
Winston-Salem, NC PMG Research of Winston-Salem United States
Recruiting
Columbus, OH Wexner Medical Center at the Ohio State University United States
Recruiting
Bountiful, UT Val Hansen United States
Not yet recruiting
Decatur, GA Atlanta Center For Gastroenterology United States
Recruiting
New Orleans, LA Ochsner Clinic Foundation United States
Recruiting
Minneapolis, MN Minnesota Gastroenterology, P.A United States
Withdrawn
Urbana, IL Carle Foundation Hospital United States
Recruiting
Seattle, WA University of Washington United States
Not yet recruiting
Richardson, TX DHAT Research Institute United States
Recruiting
Rochester, NY University of Rochester Medical Center United States
Recruiting
Asheville, NC Asheville Gastroenterology Associates United States
Recruiting
Petersburg, VA Center for Gastrointestinal Health United States
Recruiting
Pratt, KS Health Science Research Center United States
Recruiting
Greenville, NC Carolina Research United States
Not yet recruiting
Houston, TX BI Research Center United States
Not yet recruiting
Rio de Janeiro, RJ Bioclinica Inc. Research Network Brazil
Withdrawn
Amman Khalidi Hospital and Medical Center Jordan
Recruiting
Higashiibaraki-gun, 08 Mito Medical Center Japan
Recruiting
Bunkyo-ku, 13 Juntendo University Hospital Japan
Recruiting
Kuala Lumpur University Malaya Medical Centre Malaysia
Recruiting
Shreveport, LA Louisiana Research Center, LLC United States
Recruiting
Pinellas Park, FL Theia Clincial Research, LLC United States
Recruiting
Sayre, PA Guthrie Medical Group, PC United States
Withdrawn
Charleston, SC Clinical Trials of South Carolina United States
Withdrawn
Houston, TX Biopharma Informatic Research Center United States
Not yet recruiting
Tucson, AZ University of Arizona United States
Not yet recruiting
Jackson Heights, NY A1 Clinical Research United States
Recruiting
Tampa, FL Florida Hospital Tampa United States
Recruiting
Channelview, TX Aztec Clinical Research, Inc. United States
Recruiting
Temple, TX Baylor Scott & White Research Institute United States
Recruiting
Philadelphia, PA Drexel University College of Medicine United States
Not yet recruiting
Syracuse, NY Syracuse VA Medical Center United States
Not yet recruiting
Houston, TX Memorial Hermann Hospital - TMC United States
Withdrawn
Seoul Gangnam Severance Hospital South Korea
Recruiting
Lafayette, LA Gastroenterology Clinic of Acadiana United States
Recruiting
Tampa, FL Clinical Research of West Florida United States
Recruiting
Fort Lauderdale, FL InvesClinic, LLC United States
Recruiting
Tyler, TX Tyler Research Institute, LLC United States
Recruiting
New Orleans, LA DelRicht Research United States
Recruiting
Fukuoka-shi Fukuoka University Hospital Japan
Recruiting
Fukuoka-shi Saiseikai Fukuoka General Hospital Japan
Recruiting
Houston, TX CliniCore Houston United States
Recruiting
Niigata, 15 Niigata University Medical & Dental Hospital Japan
Suspended
Shinjuku-ku, 13 Tokyo Yamate Medical Center Japan
Recruiting
Sapporo-shi, 01 Hokkaido University Hospital Japan
Not yet recruiting
Kyoto, 26 Kyoto University Hospital Japan
Recruiting
Houston, TX Houston Methodist Hospital United States
Not yet recruiting
Houston, TX Baylor College of Medicine United States
Not yet recruiting
Maastricht, LI Academisch Ziekenhuis Maastricht Netherlands
Recruiting
Oklahoma City, OK Integris Baptist Office United States
Recruiting
Saginaw, MI Associated cardiology United States
Withdrawn
Miami, FL Visionary Investigators Network United States
Recruiting
La Jolla, CA University Of California San Diego United States
Not yet recruiting
Providence, RI LifeSpan Hospital System United States
Withdrawn
Indianapolis, IN IU Health University Hospital United States
Not yet recruiting
wenzhou, 33 The First Affiliated Hospital of Wenzhou Medical University China
Not yet recruiting
Sarajevo Clinical Center University of Sarajevo Bosnia and Herzegovina
Not yet recruiting
T'bilisi, TB LTD 'Aversi Clinic' Georgia
Recruiting
Sestroretsk City Hospital# 40 Russia
Withdrawn
Tomsk Tomsk Regional Clinical Hospital Russia
Not yet recruiting
Ypsilanti, MI Huron Gastroenterology Associates Center for Digestive Care United States
Not yet recruiting
Istanbul Sisli Etfal Egitim ve Arastirma Hospital Turkey
Recruiting
Heidelberg, BW Universitaetsklinikum Heidelberg Germany
Recruiting
Kota Bahru, KN Hospital Raja Perempuan Zainab Ii Malaysia
Recruiting
Shinjuku-ku, 13 Keio University Hospital Japan
Recruiting
Morristown, NJ Atlantic Digestive Health Institute/ Atlantic IBD Center United States
Recruiting
Beirut, BA American Universitty of Beirut Medical Center Lebanon
Recruiting
Skopje University Clinic of Gastroenterohepatology North Macedonia
Recruiting
Skopje University Clinic of Gastroenterohepatology North Macedonia
Recruiting
Ampang, SL Hospital Ampang Malaysia
Recruiting
Ankara, ANK Gulhane Egitim ve Arastirma Hastanesi Turkey
Recruiting
Skopje General City Hospital 8mi Septemvri North Macedonia
Recruiting
Victoria, TX Victoria Gastroenterology United States
Suspended
Weston, FL Cleveland Clinic Florida United States
Recruiting
Sarajevo Polyclinic Dr. Al-Tawil Bosnia and Herzegovina
Recruiting
Seoul Asan Medical Center South Korea
Recruiting
Zaporizhzhia Komunalna ustanova 'Miska likarnia №1' Ukraine
Withdrawn
Kiel, SH Universitatsklinikum Schleswig-Holstein - Kiel Germany
Recruiting
Roma Università Campus Biomedico di Roma Italy
Recruiting
Roma catholic university of sacred hearth Italy
Recruiting
Nishinomiya, 28 Hyogo College of Medicine Hospital Japan
Recruiting
Izumiotsu, 27 Izumiotsu Municipal Hospital Japan
Recruiting
Hamilton, WKO Waikato Hospital New Zealand
Recruiting
Istanbul, IST Marmara University Medical Faculty Turkey
Recruiting
Minsk City Clinical Hospital #9 Belarus
Recruiting
Fayetteville, NC Cumberland Research Associates United States
Recruiting
Nizhny Novgorod Novgorod Regional Clinical Hospital n.a. N.A. Semashko Russia
Recruiting
Ulyanovsk Ulyanovsk Regional Clinical Hospital Russia
Recruiting
Caguas San Juan Bautista School of Medicine Puerto Rico
Recruiting
Guimarães, Braga Hospital da Senhora da Oliveira Portugal
Recruiting
Linz Krankenhaus der Elisabethinen Linz Austria
Withdrawn
Beirut, BA Hotel Dieu de France Hospital Lebanon
Recruiting
Messina AOU Policlinico G.Martino Italy
Recruiting
Ulm, BW Universitätsklinikum Ulm Germany
Recruiting
Nagakute Aichi Medical University Hospital Japan
Recruiting
Santa Maria da Feira Centro Hospitalar de Entre o Douro e Vouga, E.P.E Portugal
Recruiting
Kunming First Affiliated Hospital of Kunming Medical Unversity China
Withdrawn
Hyderabad Citizen Hospital India
Suspended
Porto H. Santo António - Centro Hospitalar do Porto Portugal
Not yet recruiting
Beirut, BA Rafik Hariri University Hospital Lebanon
Recruiting
Medellin, ANT Instituto De Coloproctologia Ico S.A.S Colombia
Withdrawn
Cali, VDC CENTRO MÉDICO IMBANACO Colombia
Recruiting
Verona Policlinico G.B.Rossi Italy
Recruiting
Chiba Chiba University Hospital Japan
Recruiting
Minato-ku, 13 Kitasato Institute Hospital Biomedical Research Center, Clinical Trial Unit Japan
Recruiting
Beirut, BA Mount Lebanon Hospital Lebanon
Recruiting
Shanghai, 31 Shanghai 10th Peoples Hospital China
Withdrawn
Xiamen Zhongshan Hospital, Xiamen University China
Withdrawn
Shenyang The first hospital of China medical university China
Withdrawn
Velikiy Novgorod GUZ Novgorod Regional Clinical Hospital Russia
Recruiting
Podolsk GBUZ of Moscow Region City Clinical Hospital #3 Russia
Recruiting
Crewe Leighton Hospital United Kingdom
Suspended
West Bromwich, WMD Sandwell & West Birmingham Hospitals NHS Trust/Sandwell Gene United Kingdom
Not yet recruiting
London St George’s Healthcare NHS Trust United Kingdom
Not yet recruiting
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