A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma (MonumenTAL-1)
Last Updated January 28, 2025
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CR108920
OVERVIEW
-
Sexes Eligible for Study
all -
Age
years -
Phase
phase 22 -
Sites
Sites -
Status
Recruiting
SUMMARY
The purpose of this study is to evaluate the efficacy and safety of talquetamab in participants with relapsed or refractory multiple myeloma at the recommended Phase 2 dose(s) (RP2Ds) (Part 3).
CONDITIONS
- Hematological Malignancies
ELIGIBILITY
Inclusion Criteria:
* Documented initial diagnosis of multiple myeloma according to international myeloma working group (IMWG) diagnostic criteria
* Part 3: Measurable disease cohort A, cohort B, cohort C, and cohort D: multiple myeloma must be measurable by central laboratory as
DETAILS
LOCATIONS
Locations in:
United States, Belgium, China, France, Germany, Israel, Japan, South Korea, Netherlands, Poland, Spain
| Country (11) | City or Province (77) | Status |
| United States | Birmingham University of Alabama Birmingham |
RECRUITING
|
| United States | Little Rock University of Arkansas for Medical Sciences |
RECRUITING
|
| United States | Duarte City of Hope |
COMPLETED
|
| United States | Atlanta Emory University - Winship Cancer Institute |
RECRUITING
|
| United States | Chicago University of Chicago |
RECRUITING
|
| United States | Louisville Norton Cancer Institute |
RECRUITING
|
| United States | Ann Arbor University of Michigan Health System |
RECRUITING
|
| United States | Saint Louis Washington University School Of Medicine |
RECRUITING
|
| United States | New York NYU Langone Health |
RECRUITING
|
| United States | New York Mount Sinai Medical Center |
RECRUITING
|
| United States | Rochester University of Rochester Medical Center |
RECRUITING
|
| United States | Portland Providence Portland Medical Center |
RECRUITING
|
| United States | Nashville Tennessee Oncology |
RECRUITING
|
| Belgium | Brussels UCL - Saint Luc |
RECRUITING
|
| Belgium | Edegem UZ Antwerpen |
RECRUITING
|
| Belgium | Leuven UZ Leuven |
RECRUITING
|
| Belgium | Liège CHU de Liège - Domaine Universitaire du Sart Tilman |
RECRUITING
|
| China | Beijing Peking University Third Hospital |
RECRUITING
|
| China | Guangzhou Sun Yat-Sen University Cancer Center |
RECRUITING
|
| China | Hangzhou The 1St Affiliated Hospital of Medical College Zhejiang University |
ACTIVE_NOT_RECRUITING
|
| China | Hangzhou The 1St Affiliated Hospital of Medical College Zhejiang University |
RECRUITING
|
| China | Su Zhou First Affiliated Hospital SooChow University |
RECRUITING
|
| China | Tianjin Institute of Hematology & Blood Disease Hospital Chinese Academy of Medical Science |
RECRUITING
|
| China | XI An Shi The First Affiliated Hospital of Xian Jiaotong University |
RECRUITING
|
| China | Xi'an The Second Affiliated Hospital of Xi'an Jiaotong University |
COMPLETED
|
| France | Creteil CHU Henri Mondor |
RECRUITING
|
| France | Montpellier CHU de Montpellier Hopital Saint Eloi |
RECRUITING
|
| France | Nantes C.H.U. Hotel Dieu - France |
RECRUITING
|
| France | Pessac cedex CHU de Bordeaux - Hospital Haut-Leveque |
RECRUITING
|
| France | Pierre Benite cedex Centre hospitalier Lyon-Sud |
RECRUITING
|
| France | Toulouse cedex 9 Pôle IUC Oncopole CHU |
RECRUITING
|
| Germany | Berlin Charite Campus Benjamin Franklin |
RECRUITING
|
| Germany | Heidelberg Universitaetsklinikum Heidelberg |
RECRUITING
|
| Germany | Muenster Universitaetsklinikum Muenster |
COMPLETED
|
| Germany | Wuerzburg Universitatsklinikum Wurzburg |
RECRUITING
|
| Israel | Haifa Rambam Medical Center |
RECRUITING
|
| Israel | Haifa Carmel Medical Center |
RECRUITING
|
| Israel | Jerusalem Hadassah Medical Center |
RECRUITING
|
| Israel | Ramat Gan Sheba Medical Center |
RECRUITING
|
| Israel | Tel Aviv Tel Aviv Sourasky Medical Center |
RECRUITING
|
| Japan | Chiba Kameda Medical Center |
ACTIVE_NOT_RECRUITING
|
| Japan | Fukuoka Fukuoka University Hospital |
ACTIVE_NOT_RECRUITING
|
| Japan | Gifu Ogaki Municipal Hospital |
ACTIVE_NOT_RECRUITING
|
| Japan | Hokkaido Teine Keijinkai Hospital |
ACTIVE_NOT_RECRUITING
|
| Japan | Kobe City Kobe City Medical Center General Hospital |
ACTIVE_NOT_RECRUITING
|
| Japan | Koshigaya Dokkyo Medical University Saitama Medical Center |
ACTIVE_NOT_RECRUITING
|
| Japan | Kumamoto Kumamoto University Hospital |
ACTIVE_NOT_RECRUITING
|
| Japan | Kurashiki Kurashiki Central Hospital |
ACTIVE_NOT_RECRUITING
|
| Japan | Matsumoto National Hospital Organization Matsumoto Medical Center |
ACTIVE_NOT_RECRUITING
|
| Japan | Okayama National Hospital Organization Okayama Medical Center |
ACTIVE_NOT_RECRUITING
|
| Japan | Osaka Japanese Red Cross Osaka Hospital |
ACTIVE_NOT_RECRUITING
|
| Japan | Otake Hiroshima West Medical Center |
ACTIVE_NOT_RECRUITING
|
| Japan | Shiwa-gun Iwate Medical University Hospital |
ACTIVE_NOT_RECRUITING
|
| South Korea | Jeollanam-do Chonnam National University Hwasun Hospital |
RECRUITING
|
| South Korea | Seoul Seoul National University Hospital |
RECRUITING
|
| South Korea | Seoul Severance Hospital Yonsei University Health System |
COMPLETED
|
| South Korea | Seoul Asan Medical Center |
COMPLETED
|
| South Korea | Seoul Samsung Medical Center |
COMPLETED
|
| South Korea | Seoul The Catholic University of Korea Seoul St Marys Hospital |
RECRUITING
|
| Netherlands | Amsterdam VU Medisch Centrum |
RECRUITING
|
| Netherlands | Utrecht UMCU |
COMPLETED
|
| Poland | Gdansk Uniwersyteckie Centrum Kliniczne |
ACTIVE_NOT_RECRUITING
|
| Poland | Gliwice Narodowy Instytut Onkologii im.Marii Sklodowskiej Curie Panstwowy Instytut BadawczyOddz. w Gliwicach |
COMPLETED
|
| Poland | Poznan Uniwersytecki Szpital Kliniczny w Poznaniu |
ACTIVE_NOT_RECRUITING
|
| Poland | Warszawa Narodowy Instytut Onkologii im Marii Sklodowskiej Curie Panstwowy Instytut Badawczy |
ACTIVE_NOT_RECRUITING
|
| Poland | Wroclaw Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu |
ACTIVE_NOT_RECRUITING
|
| Spain | Badalona Hosp. Univ. Germans Trias I Pujol |
COMPLETED
|
| Spain | Barcelona Hosp Univ Vall D Hebron |
ACTIVE_NOT_RECRUITING
|
| Spain | Barcelona Inst. Cat. Doncologia-H Duran I Reynals |
ACTIVE_NOT_RECRUITING
|
| Spain | Madrid Hosp Univ Fund Jimenez Diaz |
COMPLETED
|
| Spain | Madrid Hosp. Univ. 12 de Octubre |
ACTIVE_NOT_RECRUITING
|
| Spain | Murcia Hosp. Univ. Virgen de La Arrixaca |
ACTIVE_NOT_RECRUITING
|
| Spain | Pamplona Clinica Univ. de Navarra |
ACTIVE_NOT_RECRUITING
|
| Spain | Pozuelo de Alarcon Hosp. Quiron Madrid Pozuelo |
ACTIVE_NOT_RECRUITING
|
| Spain | Salamanca Hosp Clinico Univ de Salamanca |
ACTIVE_NOT_RECRUITING
|
| Spain | Santander Hosp. Univ. Marques de Valdecilla |
ACTIVE_NOT_RECRUITING
|
| Spain | Sevilla Hosp. Virgen Del Rocio |
COMPLETED
|
Geo Locations
33.52066, -86.80249
34.74648, -92.28959
34.13945, -117.97729
33.749, -84.38798
41.85003, -87.65005
38.25424, -85.75941
42.27756, -83.74088
38.62727, -90.19789
40.71427, -74.00597
40.71427, -74.00597
43.15478, -77.61556
45.52345, -122.67621
36.16589, -86.78444
50.85045, 4.34878
51.15662, 4.44504
50.87959, 4.70093
50.63373, 5.56749
39.9075, 116.39723
23.11667, 113.25
30.29365, 120.16142
30.29365, 120.16142
31.2982999, 120.643
39.14222, 117.17667
34.2075699, 108.94631
34.25833, 108.92861
48.78333, 2.46667
43.61092, 3.87723
47.21725, -1.55336
44.81011, -0.64129
45.7009, 4.82511
43.60426, 1.44367
52.52437, 13.41053
49.40768, 8.69079
51.96236, 7.62571
49.79391, 9.95121
32.81841, 34.9885
32.81841, 34.9885
31.76904, 35.21633
32.08227, 34.81065
32.08088, 34.78057
35.6, 140.11667
33.6, 130.41667
35.42291, 136.76039
43.41104, 142.88878
34.6913, 135.183
35.89035, 139.78916
32.80589, 130.69182
34.58333, 133.76667
36.23333, 137.96667
34.65, 133.93333
34.69374, 135.50218
34.20752, 132.22062
33.23058, 133.24871
35.056264, 127.0025403
37.566, 126.9784
37.566, 126.9784
37.566, 126.9784
37.566, 126.9784
37.566, 126.9784
52.37403, 4.88969
52.09083, 5.12222
54.35205, 18.64637
50.29761, 18.67658
52.40692, 16.92993
52.22977, 21.01178
51.1, 17.03333
41.45004, 2.24741
41.38879, 2.15899
41.38879, 2.15899
40.4165, -3.70256
40.4165, -3.70256
37.98704, -1.13004
42.81687, -1.64323
40.43293, -3.81338
40.96882, -5.66388
43.46472, -3.80444
37.38283, -5.97317
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