A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy (CARTITUDE-5)
Last Updated August 7, 2024
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CR109015
OVERVIEW
-
Gender
all -
Age
years -
Phase
phase 33 -
Sites
Sites -
Status
Recruiting
SUMMARY
CONDITIONS
- Multiple Myeloma
ELIGIBILITY
Inclusion Criteria:
* Documented diagnosis of multiple myeloma (MM) according to International Myeloma Working Group (IMWG) diagnostic criteria
* Measurable disease at screening as defined by any of the following: Serum monoclonal paraprotein (M-protein) level greater than or equ
DETAILS
LOCATIONS
Country (26) | City or Province (136) | Status |
United States | San Francisco UCSF |
COMPLETED
|
United States | New Haven Yale Cancer Center |
ACTIVE_NOT_RECRUITING
|
United States | Miami University of Miami Health System |
ACTIVE_NOT_RECRUITING
|
United States | Orlando AdventHealth Cancer Institute |
ACTIVE_NOT_RECRUITING
|
United States | Iowa City University of Iowa Hospitals & Clinics |
ACTIVE_NOT_RECRUITING
|
United States | Lexington University of Kentucky |
COMPLETED
|
United States | Louisville Norton Cancer Institute |
ACTIVE_NOT_RECRUITING
|
United States | Baltimore University Of Maryland Medical Center |
ACTIVE_NOT_RECRUITING
|
United States | Boston Beth Israel Deaconess Medical Center |
RECRUITING
|
United States | Detroit Barbara Ann Karmanos Cancer Institute |
RECRUITING
|
United States | Detroit Henry Ford Cancer Institute |
ACTIVE_NOT_RECRUITING
|
United States | New York Columbia University Medical Center |
ACTIVE_NOT_RECRUITING
|
United States | New York Memorial Sloan-Kettering Cancer Center |
ACTIVE_NOT_RECRUITING
|
United States | New York New York Presbyterian-Weill Cornell Medical College |
ACTIVE_NOT_RECRUITING
|
United States | Charlotte Levine Cancer Institute |
ACTIVE_NOT_RECRUITING
|
United States | Philadelphia Thomas Jefferson University |
ACTIVE_NOT_RECRUITING
|
United States | Pittsburgh University of Pittsburgh Medical Center |
ACTIVE_NOT_RECRUITING
|
United States | Charlottesville University of Virginia |
ACTIVE_NOT_RECRUITING
|
United States | Milwaukee Medical College Of Wisconsin |
ACTIVE_NOT_RECRUITING
|
Argentina | Buenos Aires Hospital Aleman |
ACTIVE_NOT_RECRUITING
|
Argentina | Buenos Aires Hospital Italiano de Buenos Aires |
ACTIVE_NOT_RECRUITING
|
Argentina | Cordoba Hospital Privado Centro Medico de Cordoba |
ACTIVE_NOT_RECRUITING
|
Australia | Camperdown Royal Prince Alfred Hospital |
ACTIVE_NOT_RECRUITING
|
Australia | Fitzroy St Vincents Hospital Melbourne |
ACTIVE_NOT_RECRUITING
|
Australia | Heidelberg Austin Health |
ACTIVE_NOT_RECRUITING
|
Australia | Herston Royal Brisbane and Womens Hospital |
ACTIVE_NOT_RECRUITING
|
Australia | Melbourne Alfred Health |
ACTIVE_NOT_RECRUITING
|
Australia | Melbourne Peter MacCallum Cancer Centre |
ACTIVE_NOT_RECRUITING
|
Australia | Murdoch Fiona Stanley Hospital |
ACTIVE_NOT_RECRUITING
|
Australia | Waratah Calvary Mater Newcastle Hospital |
ACTIVE_NOT_RECRUITING
|
Australia | Westmead Western Sydney Local Health District |
ACTIVE_NOT_RECRUITING
|
Austria | Graz Medizinische Universität Graz, LKH-Univ.Klinikum Graz, Klinische Abteilung für Hämatologie |
COMPLETED
|
Austria | Linz Krankenhaus der Elisabethinen Linz |
ACTIVE_NOT_RECRUITING
|
Austria | Salzburg LKH - Universitätsklinikum der PMU Salzburg |
ACTIVE_NOT_RECRUITING
|
Austria | Vienna Medical University of Vienna Universitatsklinik fur Innere Medizin I |
ACTIVE_NOT_RECRUITING
|
Belgium | Antwerp Universitair Ziekenhuis - Antwerpen |
ACTIVE_NOT_RECRUITING
|
Belgium | Brugge AZ St.-Jan Brugge-Oostende AV |
ACTIVE_NOT_RECRUITING
|
Belgium | Gent UZ Gent |
COMPLETED
|
Belgium | Leuven UZ Leuven |
COMPLETED
|
Belgium | Liege Centre Hospitalier Universitaire de Liege Domaine Universitaire du Sart Tilman |
COMPLETED
|
Brazil | Salvador Hospital Sao Rafael |
ACTIVE_NOT_RECRUITING
|
Brazil | Sao Paulo Fundacao Antonio Prudente A C Camargo Cancer Center |
ACTIVE_NOT_RECRUITING
|
Brazil | São Paulo Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein |
ACTIVE_NOT_RECRUITING
|
Canada | Calgary Tom Baker Cancer Centre |
ACTIVE_NOT_RECRUITING
|
Canada | Vancouver Vancouver General Hospital |
ACTIVE_NOT_RECRUITING
|
Canada | Hamilton Juravinski Cancer Centre |
ACTIVE_NOT_RECRUITING
|
Canada | Toronto Princess Margaret Cancer Centre University Health Network |
ACTIVE_NOT_RECRUITING
|
Canada | Montréal Hopital Maisonneuve-Rosemont |
ACTIVE_NOT_RECRUITING
|
Czechia | Brno Fakultni nemocnice Brno |
ACTIVE_NOT_RECRUITING
|
Czechia | Hradec Kralove Fakultni nemocnice Hradec Kralove |
ACTIVE_NOT_RECRUITING
|
Czechia | Ostrava - Poruba Fakultni Nemocnice Ostrava |
ACTIVE_NOT_RECRUITING
|
Czechia | Praha 2 Vseobecna fakultni nemocnice v Praze |
ACTIVE_NOT_RECRUITING
|
Denmark | Aarhus C Aarhus University Hospital |
ACTIVE_NOT_RECRUITING
|
Denmark | Copenhagen Rigshospitalet |
ACTIVE_NOT_RECRUITING
|
Denmark | Odense C Odense Universitetshospital |
ACTIVE_NOT_RECRUITING
|
Finland | Helsinki Helsinki University Hospital |
ACTIVE_NOT_RECRUITING
|
Finland | Oulu Oulu University Hospital |
ACTIVE_NOT_RECRUITING
|
Finland | Turku Turku University Hospital |
ACTIVE_NOT_RECRUITING
|
France | Lille Cedex Centre Hospitalier Régional Universitaire de Lille, Hôpital Claude Huriez |
ACTIVE_NOT_RECRUITING
|
France | Nantes C.H.U. Hotel Dieu - France |
COMPLETED
|
France | Paris cedex 10 Hopital Saint Louis |
ACTIVE_NOT_RECRUITING
|
France | Poitiers CHU Poitiers - Hopital la Miletrie |
ACTIVE_NOT_RECRUITING
|
France | Toulouse cedex 9 Institut Universitaire du cancer de Toulouse-Oncopole |
ACTIVE_NOT_RECRUITING
|
Germany | Berlin Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin |
ACTIVE_NOT_RECRUITING
|
Germany | Dresden Universitaetsklinikum Carl Gustav Carus TU Dresden |
ACTIVE_NOT_RECRUITING
|
Germany | Freiburg Universitatsklinikum Freiburg |
ACTIVE_NOT_RECRUITING
|
Germany | Hamburg Universitaetsklinikum Hamburg Eppendorf |
ACTIVE_NOT_RECRUITING
|
Germany | Heidelberg Universitaetsklinikum Heidelberg |
ACTIVE_NOT_RECRUITING
|
Germany | Leipzig Universitaetsklinikum Leipzig |
ACTIVE_NOT_RECRUITING
|
Germany | Mainz Universitätsmedizin der Johannes Gutenberg-Universität Mainz |
ACTIVE_NOT_RECRUITING
|
Germany | München Klinikum Großhadern der Ludwig-Maximilians-Universität |
ACTIVE_NOT_RECRUITING
|
Germany | Regensburg Universitaetsklinikum Regensburg |
ACTIVE_NOT_RECRUITING
|
Germany | Tubingen Klinikum der Eberhard Karls Universitaet Abt fur innere Med II Haematologie Onkologie Germany |
ACTIVE_NOT_RECRUITING
|
Germany | Wuerzburg Universitatsklinikum Wurzburg |
ACTIVE_NOT_RECRUITING
|
Greece | Athens Alexandra General Hospital of Athens |
ACTIVE_NOT_RECRUITING
|
Greece | Athens Attikon University General Hospital of Attica |
ACTIVE_NOT_RECRUITING
|
Greece | Thessaloniki G.Papanikolaou |
ACTIVE_NOT_RECRUITING
|
Hungary | Budapest Del Pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet Szent Laszlo Telephely |
RECRUITING
|
Hungary | Debrecen Debreceni Egyetem Klinikai Kozpont |
COMPLETED
|
Ireland | Dublin St James Hospital |
RECRUITING
|
Israel | Jerusalem Hadassah University Hospita Ein Kerem |
ACTIVE_NOT_RECRUITING
|
Israel | Ramat Gan Sheba Medical Center Tel Hashomer |
ACTIVE_NOT_RECRUITING
|
Israel | Tel Aviv Tel Aviv Sourasky Medical Center |
ACTIVE_NOT_RECRUITING
|
Japan | Bunkyo Ku Juntendo University Hospital |
ACTIVE_NOT_RECRUITING
|
Japan | Fukuoka Kyushu University Hospital |
ACTIVE_NOT_RECRUITING
|
Japan | Hyôgo Hyogo Medical University Hospital |
ACTIVE_NOT_RECRUITING
|
Japan | Kanazawa Kanazawa University Hospital |
ACTIVE_NOT_RECRUITING
|
Japan | Kyoto University Hospital Kyoto Prefectural University of Medicine |
ACTIVE_NOT_RECRUITING
|
Japan | Nagoya Nagoya City University Hospital |
COMPLETED
|
Japan | Okayama Okayama University Hospital |
ACTIVE_NOT_RECRUITING
|
Japan | Sapporo Hokkaido University Hospital |
ACTIVE_NOT_RECRUITING
|
Japan | Sendai Tohoku University Hospital |
ACTIVE_NOT_RECRUITING
|
Japan | Shibuya Japanese Red Cross Medical Center |
ACTIVE_NOT_RECRUITING
|
South Korea | Jeollanam-do Chonnam National University Hwasun Hospital |
ACTIVE_NOT_RECRUITING
|
South Korea | Seoul Seoul National University Hospital |
ACTIVE_NOT_RECRUITING
|
South Korea | Seoul Severance Hospital Yonsei University Health System |
ACTIVE_NOT_RECRUITING
|
South Korea | Seoul Asan Medical Center |
ACTIVE_NOT_RECRUITING
|
South Korea | Seoul Samsung Medical Center |
ACTIVE_NOT_RECRUITING
|
South Korea | Seoul The Catholic University of Korea Seoul St Marys Hospital |
ACTIVE_NOT_RECRUITING
|
Netherlands | Amsterdam VU Medisch Centrum |
COMPLETED
|
Netherlands | Groningen University Medical Center Groningen |
ACTIVE_NOT_RECRUITING
|
Netherlands | Nijmegen UMC Radboud |
ACTIVE_NOT_RECRUITING
|
Netherlands | Rotterdam Erasmus MC |
ACTIVE_NOT_RECRUITING
|
Norway | Oslo Oslo universitetssykehus HF, Rikshospitalet |
ACTIVE_NOT_RECRUITING
|
Poland | Gdansk Uniwersyteckie Centrum Kliniczne |
ACTIVE_NOT_RECRUITING
|
Poland | Gliwice Narodowy Instytut Onkologii im.Marii Sklodowskiej Curie Panstwowy Instytut BadawczyOddz. w Gliwicach |
ACTIVE_NOT_RECRUITING
|
Poland | Lublin Centrum Onkologii Ziemi Lubelskiej im. sw. Jana z Dukli |
ACTIVE_NOT_RECRUITING
|
Poland | Poznan Uniwersytecki Szpital Kliniczny w Poznaniu |
ACTIVE_NOT_RECRUITING
|
Poland | Warszawa Instytut Hematologii i Transfuzjologii |
ACTIVE_NOT_RECRUITING
|
Poland | Wroclaw Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu |
ACTIVE_NOT_RECRUITING
|
Portugal | Lisboa Instituto Portugues de Oncologia |
ACTIVE_NOT_RECRUITING
|
Portugal | Porto Instituto Portugues de Oncologia |
ACTIVE_NOT_RECRUITING
|
Spain | Barcelona Hosp. de La Santa Creu I Sant Pau |
ACTIVE_NOT_RECRUITING
|
Spain | Barcelona Hosp Univ Vall D Hebron |
ACTIVE_NOT_RECRUITING
|
Spain | L'Hospitalet de Llobregat Instituto Catalan Deoncologia Hospital Duran I Reynals |
ACTIVE_NOT_RECRUITING
|
Spain | Madrid Hosp. Gral. Univ. Gregorio Maranon |
ACTIVE_NOT_RECRUITING
|
Spain | Madrid Hosp. Univ. 12 de Octubre |
ACTIVE_NOT_RECRUITING
|
Spain | Murcia Hosp. Univ. Virgen de La Arrixaca |
ACTIVE_NOT_RECRUITING
|
Spain | Pamplona Clinica Univ. de Navarra |
ACTIVE_NOT_RECRUITING
|
Spain | Salamanca Hosp Clinico Univ de Salamanca |
ACTIVE_NOT_RECRUITING
|
Spain | Santander Hosp. Univ. Marques de Valdecilla |
ACTIVE_NOT_RECRUITING
|
Spain | Sevilla Hosp. Virgen Del Rocio |
ACTIVE_NOT_RECRUITING
|
Spain | Valencia Hosp. Univ. I Politecni La Fe |
ACTIVE_NOT_RECRUITING
|
Sweden | Goteborg Sahlgrenska University Hospital |
COMPLETED
|
Sweden | Linköping Universitetssjukhuset |
ACTIVE_NOT_RECRUITING
|
Sweden | Lund Skane University Hospital |
ACTIVE_NOT_RECRUITING
|
Switzerland | Basel Universitatsspital Basel |
RECRUITING
|
Switzerland | Bern INSELSPITAL Universitatsspital Bern |
RECRUITING
|
Switzerland | St. Gallen Kantonsspital St Gallen |
RECRUITING
|
United Kingdom | Birmingham University Hospitals Birmingham NHS Trust, |
ACTIVE_NOT_RECRUITING
|
United Kingdom | Bristol Bristol Royal Infirmary |
ACTIVE_NOT_RECRUITING
|
United Kingdom | Leeds, Leeds Teaching Hospitals NHS Trust |
ACTIVE_NOT_RECRUITING
|
United Kingdom | London University College Hospital |
ACTIVE_NOT_RECRUITING
|
United Kingdom | London Kings College Hospital |
ACTIVE_NOT_RECRUITING
|
United Kingdom | Manchester Manchester Royal Infirmary |
ACTIVE_NOT_RECRUITING
|
United Kingdom | Surrey The Royal Marsden NHS Trust Sutton |
ACTIVE_NOT_RECRUITING
|
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