Inclusion Criteria:

* Have a documented diagnosis of multiple myeloma according to International myeloma working group (IMWG) diagnostic criteria

* Received at least 3 prior lines of therapy (induction with or without hematopoietic stem cell transplant and with or without maintenance therapy is considered a single regimen). Undergone at least 1 complete cycle of treatment for each line of therapy, unless progressive disease (PD) was the best response to the line of therapy

* Have an Eastern Cooperative Oncology Group (ECOG) Performance Status grade of 0 or 1

* Must not be pregnant or must not plan to become pregnant within the study period

* Must have documented evidence of progressive disease based on participating physician's determination of response by the IMWG response criteria on or after the last regimen. Participants with documented evidence of progressive disease within the previous 6 months and who are refractory or non-responsive to their most recent line of treatment afterwards are also eligible