A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease (FUZION CD)
Last Updated May 10, 2025
Want to learn how to participate in this trial?
CR109189
OVERVIEW
-
Sexes Eligible for Study
all -
Age
years -
Phase
phase 33 -
Sites
Sites -
Status
Recruiting
SUMMARY
The purpose of this study to evaluate the clinical efficacy of guselkumab in fistulizing, perianal Crohn's disease and to assess the overall safety of guselkumab.
CONDITIONS
- Fistulizing Crohns Disease
- Perianal Crohns Disease
ELIGIBILITY
Inclusion Criteria:
* Must have a diagnosis of Crohn's disease with a minimum duration of at least 3 months
* Has at least one active draining perianal fistula as a complication of Crohn's disease, confirmed by screening magnetic resonance imaging (MRI) results
* Has previousl
DETAILS
LOCATIONS
Locations in:
United States, Australia, Belgium, Canada, Czechia, France, Germany, Greece, Hungary, Israel, Italy, Japan, Jordan, South Korea, Netherlands, Poland, Portugal, Saudi Arabia, Spain, Taiwan, Türkiye, United Kingdom, Egypt
| Country (23) | City or Province (153) | Status |
| United States | Birmingham University of Alabama at Birmingham |
COMPLETED
|
| United States | Naples Gastroenterology Group Of Naples |
RECRUITING
|
| United States | Orlando AdventHealth Medical Group Blood & Marrow Transplant at Orlando |
RECRUITING
|
| United States | Kansas City Kansas University Medical Center |
RECRUITING
|
| United States | Louisville University of Louisville |
RECRUITING
|
| United States | New York Mount Sinai School of Medicine |
RECRUITING
|
| United States | Oklahoma City Digestive Disease Specialists Inc |
COMPLETED
|
| United States | Germantown Gastro One |
RECRUITING
|
| United States | Tyler Tyler Research Institute, LLC |
RECRUITING
|
| United States | Seattle Swedish Medical Center |
RECRUITING
|
| Australia | Adelaide Flinders Medical Centre |
RECRUITING
|
| Australia | Fitzroy St Vincent's Hospital - Melbourne |
RECRUITING
|
| Australia | Murdoch Fiona Stanley Hospital |
RECRUITING
|
| Australia | Newtown Royal Prince Alfred Hospital |
RECRUITING
|
| Australia | North Terrace Royal Adelaide Hospital |
RECRUITING
|
| Australia | Parkville Royal Melbourne Hospital |
RECRUITING
|
| Australia | Perth Royal Perth Hospital |
RECRUITING
|
| Australia | South Brisbane Mater Hospital |
RECRUITING
|
| Belgium | Leuven UZ Leuven |
RECRUITING
|
| Belgium | Liege CHU Sart Tilman |
RECRUITING
|
| Canada | Edmonton University of Alberta- Ziedler Ledcor Centre |
RECRUITING
|
| Canada | London London Health Sciences Centre |
RECRUITING
|
| Canada | Toronto Mount Sinai Hospital |
RECRUITING
|
| Canada | Montreal McGill University Health Centre |
RECRUITING
|
| Czechia | Ceske Budejovice Nemocnice Ceske Budejovice a s |
RECRUITING
|
| France | Neuilly-sur-Seine Clinique Ambroise Pare |
RECRUITING
|
| France | Pierre-Benite Centre Hospitalier Lyon Sud |
RECRUITING
|
| France | Rennes CHRU Hopital de Pontchaillou |
RECRUITING
|
| France | Vandoeuvre les Nancy CHRU Nancy Brabois |
RECRUITING
|
| Germany | Berlin Charite - Campus Mitte |
RECRUITING
|
| Germany | Frankfurt JWG-University Hospital |
RECRUITING
|
| Germany | Mannheim Universitaetsklinikum Mannheim |
RECRUITING
|
| Greece | Athens Evangelismos General Hospital of Athens |
RECRUITING
|
| Greece | Athens Hippokration Hospital |
RECRUITING
|
| Greece | Heraklion University Hospital of Heraklion |
RECRUITING
|
| Greece | Patras Patras University Hospital |
RECRUITING
|
| Hungary | Budapest Magyar Honvedseg Egeszsegugyi Kozpont |
RECRUITING
|
| Hungary | Budapest Semmelweis Egyetem |
RECRUITING
|
| Hungary | Budapest Semmelweis Egyetem |
RECRUITING
|
| Israel | Haifa Rambam Medical Center |
RECRUITING
|
| Israel | Jerusalem Shaare Zedek Medical Center |
RECRUITING
|
| Israel | Petah Tikva Rabin Medical Center Beilinson Campus |
RECRUITING
|
| Italy | Milano Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico |
RECRUITING
|
| Italy | Negrar ( Ve) Ospedale Classificato Equiparato Sacro Cuore Don Calabria di Negrar |
RECRUITING
|
| Italy | Pisa Azienda Ospedaliera Universitaria Pisana |
RECRUITING
|
| Italy | San Giovanni Rotondo Casa Sollievo della Sofferenza |
RECRUITING
|
| Japan | Abiko KOKIKAI Tokatsu Tsujinaka Hospital |
RECRUITING
|
| Japan | Chikushino-shi Fukuoka University Chikushi Hospital |
RECRUITING
|
| Japan | Fukuoka-ken Kitakyushu Municipal Medical Center |
RECRUITING
|
| Japan | Hiroshima shi Hiroshima University Hospital |
RECRUITING
|
| Japan | Kagoshima Sameshima Hospital |
RECRUITING
|
| Japan | Kashihara Nara Medical University Hospital |
RECRUITING
|
| Japan | Kashiwa Tsujinaka Hospital Kashiwanoha |
RECRUITING
|
| Japan | Nagasaki Nagasaki University Hospital |
RECRUITING
|
| Japan | Nishinomiya The Hospital of Hyogo College of Medicine |
RECRUITING
|
| Japan | Shinjuku-ku Tokyo Yamate Medical Center |
RECRUITING
|
| Japan | Shizuoka Matsuda Hospital |
RECRUITING
|
| Japan | Suita Osaka University Hospital |
RECRUITING
|
| Japan | Tokyo Kyorin University Hospital |
RECRUITING
|
| Japan | Toyota Ieda Hospital |
RECRUITING
|
| Japan | Tsu Mie University Hospital |
RECRUITING
|
| Japan | Yokkaichi Yokkaichi Hazu Medical Center |
RECRUITING
|
| Jordan | Amman The Speciality Hospital (TSH) / Advanced Clinical Center |
RECRUITING
|
| Jordan | Amman Jordan University Hospital |
RECRUITING
|
| Jordan | Amman Abdali Hospital |
RECRUITING
|
| Jordan | Irbid Irbid Specialty Hospital |
RECRUITING
|
| Jordan | Irbid King Abdullah University Hospital |
RECRUITING
|
| South Korea | Seoul Seoul National University Hospital |
RECRUITING
|
| South Korea | Seoul Gangnam Severance Hospital, Yonsei University Health System |
RECRUITING
|
| Netherlands | Amsterdam Academisch Medisch Centrum Universiteit van Amsterdam |
RECRUITING
|
| Netherlands | Nijmegen Radboudumc |
RECRUITING
|
| Netherlands | Utrecht UMC Utrecht |
COMPLETED
|
| Poland | Bialystok Gastromed Kralisz Romatowski Stachurska Sp. j. |
RECRUITING
|
| Poland | Krakow Centrum Medyczne Promed |
RECRUITING
|
| Poland | Rzeszow Centrum Medyczne Medyk |
RECRUITING
|
| Poland | Szczecin Twoja Przychodnia - Szczecinskie Centrum Medyczne |
RECRUITING
|
| Poland | Warszawa WIP Warsaw IBD Point Profesor Kierkus |
RECRUITING
|
| Poland | Wroclaw Melita Medical Sp. z o.o. |
RECRUITING
|
| Portugal | Porto H. Santo António - Centro Hospitalar do Porto |
RECRUITING
|
| Saudi Arabia | Dammam King Fahad Specialist hospital |
RECRUITING
|
| Saudi Arabia | Jeddah King Abdulaziz Medical City |
RECRUITING
|
| Saudi Arabia | Riyadh King Saud University Medical City |
RECRUITING
|
| Saudi Arabia | Riyadh King Faisal Specialist Hospital & Research Center |
RECRUITING
|
| Spain | Barcelona Hosp Clinic de Barcelona |
RECRUITING
|
| Spain | Ferrol Hosp. Arquitecto Marcide |
RECRUITING
|
| Spain | Madrid Hosp. Univ. de La Princesa |
RECRUITING
|
| Spain | Majadahonda Hosp. Univ. Pta. de Hierro Majadahonda |
RECRUITING
|
| Spain | Sevilla Hosp. Virgen Macarena |
RECRUITING
|
| Spain | Vigo Hosp. Alvaro Cunqueiro |
RECRUITING
|
| Spain | Zaragoza Hosp. Univ. Miguel Servet |
RECRUITING
|
| Taiwan | Changhua Changhua Christian Hospital |
RECRUITING
|
| Taiwan | Taichung Taichung Veterans General Hospital |
RECRUITING
|
| Taiwan | Taipei City National Taiwan University Hospital |
RECRUITING
|
| Taiwan | Taoyuan City Chang Gung Memorial Hospital Linkou Branch |
RECRUITING
|
| Türkiye | Ankara Gazi University Medical Faculty |
RECRUITING
|
| Türkiye | Istanbul Istanbul University Cerrahpasa Medical Faculty |
RECRUITING
|
| Türkiye | Istanbul Acibadem Kozyatagi Hospital |
RECRUITING
|
| Türkiye | İzmir Ege University Medical Faculty |
RECRUITING
|
| Türkiye | Mersin Mersin University Medical Faculty Hospital |
RECRUITING
|
| United Kingdom | Hull Hull University Teaching Hospitals NHS Trust |
RECRUITING
|
| United Kingdom | London London North West University Healthcare NHS Trust |
RECRUITING
|
| United Kingdom | London St George's University Hospital NHS Foundation Trust |
RECRUITING
|
| United Kingdom | Newcastle Upon Tyne Newcastle upon Tyne Hospitals NHS Foundation Trust |
RECRUITING
|
| United Kingdom | Salford Pennine Acute Hospitals NHS Trust |
RECRUITING
|
| United States | Saint Louis Washington University School Of Medicine |
COMPLETED
|
| Germany | Ulm Universitaetsklinikum Ulm |
RECRUITING
|
| Japan | Nagoya Nagoya University Hospital |
RECRUITING
|
| Spain | Girona Hosp. Univ. Dr. Josep Trueta |
RECRUITING
|
| United States | New Haven Yale University |
COMPLETED
|
| United States | Miami University of Miami |
COMPLETED
|
| United States | Lexington University of Kentucky Chandler Medical Center |
COMPLETED
|
| United States | Nashville Vanderbilt University Medical Center |
COMPLETED
|
| Australia | Liverpool Liverpool Hospital |
COMPLETED
|
| Belgium | Bruxelles Hopital Erasme |
COMPLETED
|
| Belgium | Genk Ziekenhuis Oost-Limburg |
COMPLETED
|
| Canada | Halifax Nova Scotia Health Authority |
COMPLETED
|
| Czechia | Praha 9 ISCARE a.s. |
COMPLETED
|
| Egypt | Alexandria Alexandria University Hospital |
RECRUITING
|
| Egypt | Cairo National Hepatology and Tropical Medicine Research Institute |
RECRUITING
|
| Egypt | Cairo Ain Shams University Hospital |
RECRUITING
|
| Egypt | Giza Cairo university |
RECRUITING
|
| France | Nice CHU de Nice Hopital de l Archet |
COMPLETED
|
| France | Paris Hopital Saint Joseph |
COMPLETED
|
| Germany | Kiel Universitatsklinikum Schleswig Holstein Kiel |
COMPLETED
|
| Greece | Athens Attica Alexandra General Hospital of Athens |
RECRUITING
|
| Greece | Athens Sotiria General State Hospital of Chest Diseases |
RECRUITING
|
| Greece | Larissa University Hospital Of Larissa |
RECRUITING
|
| Greece | Thessaloniki Hippokration Hospital |
RECRUITING
|
| Hungary | Budapest Semmelweis Egyetem |
COMPLETED
|
| Hungary | Pecs Pecsi Tudomanyegyetem Orvostudomanyi Es Egeszsegtudomanyi Centrum, I. Belgyogyaszati Klinika |
COMPLETED
|
| Hungary | Szeged Szegedi Tud Egyetem Szent Gyorgyi Albert Klin Kozp |
RECRUITING
|
| Israel | Afula Haemek Medical Center |
RECRUITING
|
| Italy | RHO Azienda Ospedaliera G.Salvini Ospedale di Rho |
COMPLETED
|
| Italy | Roma Policlinico Universitario Agostino Gemelli |
RECRUITING
|
| Italy | Rozzano Istituto Clinico Humanitas |
RECRUITING
|
| Japan | Fukuoka Fukuoka University Hospital |
COMPLETED
|
| Japan | Hukuoka Hospital of the University of Occupational and Enviromental Health |
COMPLETED
|
| Japan | Nagoya Kojunkai Daido Clinic |
COMPLETED
|
| Japan | Okayama Okayama University Hospital |
RECRUITING
|
| Japan | Osaka Kinshukai Infusion Clinic |
COMPLETED
|
| Japan | Sakai JOHAS Osaka Rosai Hospital |
COMPLETED
|
| Japan | Sapporo Sapporo Higashi Tokushukai Hospital |
COMPLETED
|
| Japan | Yokohama Yokohama Municipal Citizen's Hospital |
COMPLETED
|
| South Korea | Busan Inje University Haeundae Paik Hospital |
COMPLETED
|
| South Korea | Daegu Yeungnam University Hospital |
COMPLETED
|
| South Korea | Gyeonggi-do Seoul National University Bundang Hospital |
COMPLETED
|
| Netherlands | Rotterdam Erasmus MC |
COMPLETED
|
| Poland | Lodz Centrum Medyczne Med Gastr |
RECRUITING
|
| Poland | Torun GASTROMED Kopon Zmudzinski i wspolnicy SP j Specjalistyczne Centrum Gastrologii i Endoskopii |
RECRUITING
|
| Poland | Wroclaw Centrum Medyczne Oporow |
RECRUITING
|
| Portugal | Braga Uls Braga - Hosp. Braga |
RECRUITING
|
| Portugal | Lisboa Uls Sao Jose - Hosp. Sto Antonio Dos Capuchos |
COMPLETED
|
| United Kingdom | London Guys and St Thomas NHS Foundation Trust |
RECRUITING
|
Geo Locations
33.52066, -86.80249
26.14234, -81.79596
28.53834, -81.37924
39.11417, -94.62746
38.25424, -85.75941
40.71427, -74.00597
35.46756, -97.51643
35.08676, -89.81009
32.35126, -95.30106
47.60621, -122.33207
-34.92866, 138.59863
-37.79839, 144.97833
-32.06987, 115.83757
-33.89835, 151.17754
-34.9211946, 138.6053204
-37.78333, 144.95
-31.95224, 115.8614
-27.48034, 153.02049
50.87959, 4.70093
50.63373, 5.56749
53.55014, -113.46871
42.98339, -81.23304
43.70011, -79.4163
45.50884, -73.58781
48.97447, 14.47434
48.8846, 2.26965
45.7009, 4.82511
48.11198, -1.67429
48.65, 6.18333
52.52437, 13.41053
50.11552, 8.68417
49.4891, 8.46694
37.97945, 23.71622
37.97945, 23.71622
35.32787, 25.14341
38.24444, 21.73444
47.49801, 19.03991
47.49801, 19.03991
47.49801, 19.03991
32.81841, 34.9885
31.76904, 35.21633
32.08707, 34.88747
45.46427, 9.18951
45.5392619, 10.9543613
43.70853, 10.4036
41.70643, 15.7277
35.86667, 140.01667
33.49631, 130.5156
33.6, 130.41667
34.4, 132.45
31.56667, 130.55
34.50896, 135.7929
35.86224, 139.97732
32.75, 129.88333
34.71562, 135.33199
35.2946, 139.57059
34.98333, 138.38333
34.76143, 135.51567
35.6895, 139.69171
35.08333, 137.15
34.73333, 136.51667
34.96667, 136.61667
31.95522, 35.94503
31.95522, 35.94503
31.95522, 35.94503
32.55556, 35.85
32.55556, 35.85
37.566, 126.9784
37.566, 126.9784
52.37403, 4.88969
51.8425, 5.85278
52.09083, 5.12222
53.13333, 23.16433
50.06143, 19.93658
50.04132, 21.99901
53.42894, 14.55302
52.22977, 21.01178
51.1, 17.03333
41.14961, -8.61099
26.43442, 50.10326
21.54238, 39.19797
24.68773, 46.72185
24.68773, 46.72185
41.38879, 2.15899
43.4896, -8.21942
40.4165, -3.70256
40.47353, -3.87182
37.38283, -5.97317
42.23282, -8.72264
41.65606, -0.87734
24.07327, 120.56276
24.1469, 120.6839
25.04776, 121.53185
24.95233, 121.20193
39.91987, 32.85427
41.01384, 28.94966
41.01384, 28.94966
38.41273, 27.13838
36.79526, 34.61792
53.7446, -0.33525
51.50853, -0.12574
51.50853, -0.12574
54.97328, -1.61396
53.48771, -2.29042
38.62727, -90.19789
48.39841, 9.99155
35.18147, 136.90641
41.98311, 2.82493
41.30815, -72.92816
25.77427, -80.19366
37.98869, -84.47772
36.16589, -86.78444
-33.90011, 150.93328
50.85045, 4.34878
50.965, 5.50082
44.64533, -63.57239
50.08804, 14.42076
31.21564, 29.95527
30.06263, 31.24967
30.06263, 31.24967
30.00808, 31.21093
43.70313, 7.26608
48.85341, 2.3488
54.32133, 10.13489
37.9804964, 23.7561153
37.97945, 23.71622
39.63689, 22.41761
40.64361, 22.93086
47.49801, 19.03991
46.08333, 18.23333
46.253, 20.14824
32.60907, 35.2892
45.53245, 9.0402
41.89193, 12.51133
45.38193, 9.1559
33.6, 130.41667
33.8769595, 130.7131381
35.18147, 136.90641
34.65, 133.93333
34.69374, 135.50218
34.58333, 135.46667
43.06667, 141.35
35.43333, 139.65
35.10278, 129.04028
35.87028, 128.59111
37.58944, 126.76917
51.9225, 4.47917
51.75, 19.46667
53.01375, 18.59814
51.1, 17.03333
41.55032, -8.42005
38.71667, -9.13333
51.50853, -0.12574
x
50
Indicates 50+ sites in this region: click to zoom in.
10
Indicates 10+ sites in this region: click to zoom in.
5
Indicates < 10 sites in this region: click to zoom in.
Corresponds to individual site.