A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma (MajesTEC-7)
Last Updated August 30, 2024
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CR109237
OVERVIEW
-
Sexes Eligible for Study
all -
Age
years -
Phase
phase 33 -
Sites
Sites -
Status
Recruiting
SUMMARY
The purpose of this study is to compare the efficacy of teclistamab in combination with daratumumab and lenalidomide (Tec-DR) and talquetamab in combination with daratumumab and lenalidomide (Tal-DR) versus daratumumab, lenalidomide, dexamethasone (DRd).
CONDITIONS
- Multiple Myeloma
ELIGIBILITY
Inclusion Criteria:
* Have a diagnosis of multiple myeloma according to the International Myeloma Working Group (IMWG) diagnostic criteria
* Be newly diagnosed and not considered a candidate for high-dose chemotherapy with autologous stem cell transplant (ASCT) due to: ineligible
DETAILS
LOCATIONS
Locations in:
Australia, Austria, Belgium, Brazil, Canada, China, Czechia, Denmark, France, Germany, Greece, Israel, Italy, Japan, South Korea, Netherlands, Norway, Poland, Portugal, Spain, Sweden, Switzerland, Türkiye, United Kingdom
| Country (24) | City or Province (158) | Status |
| Australia | Camperdown Royal Prince Alfred Hospital |
RECRUITING
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| Australia | Geelong Barwon Health - University Hospital Geelong |
RECRUITING
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| Australia | Liverpool Liverpool Hospital |
RECRUITING
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| Australia | New South Wales Calvary Mater Newcastle Hospital |
RECRUITING
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| Australia | Wollongong Wollongong Hospital |
RECRUITING
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| Australia | Woolloongabba Princess Alexandra Hospital |
RECRUITING
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| Austria | Linz Ordensklinikum Linz GmbH Elisabethinen |
RECRUITING
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| Austria | Salzburg SCRI CCCIT gem GmbH |
RECRUITING
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| Belgium | Anderlecht Institut Jules Bordet |
RECRUITING
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| Belgium | Gent Ghent University Hospital |
RECRUITING
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| Belgium | Haine Saint Paul La Louviere Jolimont |
COMPLETED
|
| Belgium | Kortrijk Az Groeninge |
RECRUITING
|
| Belgium | Leuven Universitair Ziekenhuis Leuven |
RECRUITING
|
| Belgium | Wilrijk GZA Ziekenhuizen- Campus St Augustinus |
COMPLETED
|
| Brazil | Barretos Fundacao Pio XII |
RECRUITING
|
| Brazil | Belo Horizonte Santa Casa de Misericordia de Belo Horizonte |
RECRUITING
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| Brazil | Curitiba Liga Paranaense de Combate ao Cancer |
RECRUITING
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| Brazil | Fortaleza Instituto Do Cancer Do Ceara |
RECRUITING
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| Brazil | Natal Liga Norte Riograndense Contra O Cancer |
RECRUITING
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| Brazil | Niteroi Complexo Hospitalar de Niteroi |
RECRUITING
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| Brazil | Porto Alegre Hospital de Clinicas de Porto Alegre |
RECRUITING
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| Brazil | Ribeirao Preto Hospital Das Clinicas Da Faculdade De Medicina De RPUSP HCRP |
RECRUITING
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| Brazil | Salvador Hospital Sao Rafael |
RECRUITING
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| Brazil | Sao Paulo Clinica Medica Sao Germano S/S LTDA |
RECRUITING
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| Brazil | Sao Paulo Hospital Das Clinicas Da Faculdade De Medicina Da USP |
RECRUITING
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| Canada | Calgary Tom Baker Cancer Center University of Calgary |
RECRUITING
|
| China | Beijing Peking University First Hospital |
RECRUITING
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| China | Changsha The Second Xiangya Hospital of Central South Hospital |
RECRUITING
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| China | Fu Zhou Fujian Meidical University Union Hospital |
RECRUITING
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| China | Guangzhou Sun Yat -Sen University Cancer Center |
RECRUITING
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| China | Jinan Qilu Hospital of Shandong University |
RECRUITING
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| China | Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine |
RECRUITING
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| China | Shanghai Shanghai Fourth People s Hospital |
RECRUITING
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| China | Tian Jin Institute of Hematology and Blood Diseases Hospital |
RECRUITING
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| China | Tianjin Tianjin Medical University Cancer Institute and Hospital |
RECRUITING
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| China | Wenzhou The First Affiliated Hospital of Wenzhou Medical University |
RECRUITING
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| China | WuHan Wuhan Tongji Hospital Tongji Medical College |
RECRUITING
|
| Czechia | Brno - Bohunice Fakultni nemocnice Brno |
RECRUITING
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| Czechia | Hradec Kralove Fakultni nemocnice Hradec Kralove |
RECRUITING
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| Czechia | Olomouc Fakultni nemocnice Olomouc |
RECRUITING
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| Czechia | Ostrava Fakultni Nemocnice Ostrava |
RECRUITING
|
| Czechia | Plzen Fakultni nemocnice Plzen |
RECRUITING
|
| Czechia | Praha VFN v Praze |
RECRUITING
|
| Denmark | Vejle Vejle Sygehus |
RECRUITING
|
| France | Creteil APHP - Hopital Henri Mondor |
RECRUITING
|
| France | Lille Hopital Claude Huriez |
RECRUITING
|
| France | Nantes CHU Nantes |
RECRUITING
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| France | PARIS cedex 12 CHU Hopital Saint Antoine |
RECRUITING
|
| France | Pessac cedex CHU de Bordeaux - Hospital Haut-Leveque |
RECRUITING
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| France | Pierre-Benite CHU Lyon Sud |
RECRUITING
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| France | Poitiers CHU Poitiers - Hopital la Miletrie |
RECRUITING
|
| France | Rennes CHU de Rennes - Hopital Pontchaillou |
RECRUITING
|
| France | Strasbourg Institut de Cancerologie Strasbourg Europe ICANS |
RECRUITING
|
| France | Toulouse Institut Universitaire du Cancer Toulouse Oncopole |
RECRUITING
|
| Germany | Berlin Helios Kliniken Berlin Buch Gmbh |
RECRUITING
|
| Germany | Halle (Saale) Universitaetsklinikum Halle Saale |
RECRUITING
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| Germany | Hamburg Universitaetsklinik Hamburg-Eppendorf |
RECRUITING
|
| Germany | Nuernberg Klinikum Nuernberg Nord |
RECRUITING
|
| Germany | Tübingen Universitaetsklinikum Tuebingen der Eberhard-Karls-Universitaet, Abteilung fuer Innere Medizin II, |
RECRUITING
|
| Germany | Wurzburg Universitaetsklinikum Wuerzburg |
RECRUITING
|
| Greece | Athens Attica Alexandra General Hospital of Athens |
RECRUITING
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| Greece | Thessalonikis G Papanikolaou Hospital of Thessaloniki |
RECRUITING
|
| Greece | Thessaloniki Anticancer Hospital of Thessaloniki Theageneio |
RECRUITING
|
| Israel | Haifa Rambam Medical Center |
RECRUITING
|
| Israel | Petah Tikva Rabin |
RECRUITING
|
| Israel | Ramat Gan Sheba Medical Center |
RECRUITING
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| Israel | Tel Aviv Yafo Tel Aviv Sourasky Medical Center |
RECRUITING
|
| Italy | Bologna A O U Sant Orsola Malpighi |
RECRUITING
|
| Italy | Firenze Careggi University Hospital |
RECRUITING
|
| Italy | Milan Ospedale San Raffaele |
RECRUITING
|
| Italy | Pavia IRCCS Policlinico San Matteo, Università degli studi di Pavi |
RECRUITING
|
| Italy | Roma Universita Degli Studi di Roma Tor Vergata |
RECRUITING
|
| Italy | Rozzano Istituto Clinico Humanitas |
RECRUITING
|
| Italy | Torino Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino |
RECRUITING
|
| Japan | Chiba Kameda Medical Center |
RECRUITING
|
| Japan | Higashiibaraki-gun National Hospital Organization Mito Medical Center |
RECRUITING
|
| Japan | Hirakata Kansai Medical University Hospital |
RECRUITING
|
| Japan | Iruma-gun Saitama Medical University Hospital |
RECRUITING
|
| Japan | Kanazawa Kanazawa University Hospital |
RECRUITING
|
| Japan | Matsuyama-City Matsuyama Red Cross Hospital |
RECRUITING
|
| Japan | Okayama National Hospital Organization Okayama Medical Center |
RECRUITING
|
| Japan | Shibukawa National Hospital Organization Shibukawa Medical Center |
RECRUITING
|
| Japan | Yamagata Yamagata University Hospital |
RECRUITING
|
| Japan | Yamanashi Yamanashi Prefectural Central Hospital |
RECRUITING
|
| South Korea | Busan Dong-A University Hospital |
RECRUITING
|
| South Korea | Busan Pusan National University Hospital |
RECRUITING
|
| South Korea | Goyang si National Cancer Center |
RECRUITING
|
| South Korea | Hwasun Chonnam National University Hwasun Hospital |
RECRUITING
|
| South Korea | Incheon Gachon University Gil Medical Center |
RECRUITING
|
| South Korea | Seoul Seoul National University Hospital |
RECRUITING
|
| South Korea | Seoul Severance Hospital Yonsei University Health System |
RECRUITING
|
| South Korea | Seoul Asan Medical Center |
RECRUITING
|
| South Korea | Seoul Samsung Medical Center |
RECRUITING
|
| South Korea | Seoul The Catholic University of Korea Seoul St Mary s Hospital |
RECRUITING
|
| Netherlands | Amsterdam VUMC Amsterdam |
RECRUITING
|
| Netherlands | Apeldoorn Gelre Ziekenhuis |
RECRUITING
|
| Netherlands | Nieuwegein St. Antonius Ziekenhuis Nieuwegein |
RECRUITING
|
| Netherlands | Sittard-Geleen Zuyderland Medical Center |
RECRUITING
|
| Norway | Oslo Oslo University Hospital HF Ulleval sykehus |
RECRUITING
|
| Norway | Trondheim St. Olavs Hospital |
RECRUITING
|
| Poland | Brzozow Szpital Specjalistyczny w Brzozowie Podkarpacki Osrodek Onkologiczny im Ks B Markiewicza |
RECRUITING
|
| Poland | Kielce Swietokrzyskie Centrum Onkologii SPZOZ w Kielcach |
RECRUITING
|
| Portugal | Braga Ccab - Hosp. de Braga |
RECRUITING
|
| Portugal | Lisbon Champalimaud Foundation Champalimaud Centre |
RECRUITING
|
| Portugal | Porto Uls Hosp Sao Joao |
RECRUITING
|
| Spain | Badalona Hosp. Univ. Germans Trias I Pujol |
RECRUITING
|
| Spain | Barcelona Hosp. de La Santa Creu I Sant Pau |
RECRUITING
|
| Spain | Barcelona Hosp Univ Vall D Hebron |
RECRUITING
|
| Spain | Granada Hosp. Univ. Virgen de Las Nieves |
RECRUITING
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| Spain | Jerez de la Frontera Hosp. de Jerez de La Frontera |
RECRUITING
|
| Spain | Madrid Hosp. Univ. 12 de Octubre |
RECRUITING
|
| Spain | Madrid Hosp. Univ. La Paz |
RECRUITING
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| Spain | Madrid Hosp Univ Hm Sanchinarro |
RECRUITING
|
| Spain | Palma de Mallorca Hosp. Univ. Son Espases |
RECRUITING
|
| Spain | Salamanca Hosp Clinico Univ de Salamanca |
RECRUITING
|
| Spain | Terrassa Hosp. Mutua Terrassa |
RECRUITING
|
| Spain | Valencia Hosp. Clinico Univ. de Valencia |
RECRUITING
|
| Sweden | Falun Falu Lasarett |
RECRUITING
|
| Sweden | Lund Skanes universitetssjukhus |
RECRUITING
|
| Sweden | Stockholm Karolinska University Hospital Huddinge |
RECRUITING
|
| Sweden | Örebro Universitetssjukhuset Orebro |
RECRUITING
|
| Switzerland | Bern INSELSPITAL Universitatsspital Bern |
RECRUITING
|
| Switzerland | St. Gallen Kantonsspital St Gallen |
RECRUITING
|
| Türkiye | Ankara Dr Abdurrahman Yurtaslan Oncology Training and Research Hospital |
RECRUITING
|
| Türkiye | Ankara Ankara University Medical Faculty |
RECRUITING
|
| Türkiye | Ankara Liv Hospital Ankara |
RECRUITING
|
| Türkiye | Denizli Pamukkale University Medical Faculty |
RECRUITING
|
| Türkiye | Istanbul Medipol University Hospital |
RECRUITING
|
| Türkiye | Izmir Dokuz Eylul University Medical Faculty |
COMPLETED
|
| Türkiye | Samsun Ondokuz Mayis University |
RECRUITING
|
| United Kingdom | Blackpool Blackpool Victoria Hospital |
RECRUITING
|
| United Kingdom | Canterbury Kent and Canterbury Hospital |
RECRUITING
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| United Kingdom | Edinburgh Western General Hospital |
RECRUITING
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| United Kingdom | London Imperial College Healthcare |
RECRUITING
|
| Australia | Nedlands Sir Charles Gairdner Hospital |
RECRUITING
|
| Brazil | Sao Paulo Hospital Nove de Julho |
RECRUITING
|
| Canada | Quebec CHU de Quebec L Hotel Dieu de Quebec |
RECRUITING
|
| China | Chang Zhou Changzhou No 2 Peoples Hospital |
RECRUITING
|
| China | Changchun The First Hospital of Jilin University |
RECRUITING
|
| China | Chaoyang District Beijing Chaoyang Hospital |
RECRUITING
|
| China | Harbin Harbin medical university cancer hospital |
RECRUITING
|
| China | Nan Jing Zhongda Hospital Southeast University |
RECRUITING
|
| China | Nan Ning Shi The First Affiliated Hospital of Guangxi Medical University |
RECRUITING
|
| China | Nanchang The First Affliated Hospital Of Nanchang University |
RECRUITING
|
| China | Shanghai Ruijin Hospital Shanghai Jiao Tong University |
RECRUITING
|
| China | Shenyang Shengjing Hospital Of China Medical University |
RECRUITING
|
| Israel | Jerusalem Shaare Zedek Medical Center |
RECRUITING
|
| Japan | Bunkyo-Ku Juntendo University Hospital |
RECRUITING
|
| Japan | Chiba Chiba Cancer Center |
RECRUITING
|
| Japan | Hyôgo Hyogo Medical University Hospital |
RECRUITING
|
| Japan | Kanagawa Tokai University Hospital |
RECRUITING
|
| Japan | Kumamoto-shi Kumamoto University Hospital |
RECRUITING
|
| Japan | Nagasaki National Hospital Organization Nagasaki Medical Center |
RECRUITING
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| Japan | Osaka Osaka Metropolitan University Hospital |
RECRUITING
|
| Netherlands | Delft Reinier de Graaf Gasthuis |
RECRUITING
|
| Poland | Katowice Pratia Onkologia Katowice |
RECRUITING
|
| Spain | Pozuelo de Alarcon Hosp. Quiron Madrid Pozuelo |
RECRUITING
|
| United Kingdom | Bristol University Hospitals Bristol and Weston |
RECRUITING
|
Geo Locations
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