A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis
Last Updated May 14, 2025
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CR109046
OVERVIEW
-
Sexes Eligible for Study
all -
Age
years -
Phase
phase 3 -
Sites
Sites -
Status
Recruiting
SUMMARY
The purpose of this study is to evaluate the efficacy and safety of nipocalimab compared to placebo in participants with generalized myasthenia gravis (gMG).
CONDITIONS
- Myasthenia Gravis
ELIGIBILITY
Inclusion Criteria:
* Diagnosis of myasthenia gravis (MG) with generalized muscle weakness meeting the clinical criteria for generalized myasthenia gravis (gMG) as defined by the Myasthenia Gravis Foundation of America (MGFA) Clinical Classification Class II a/b, III a/b, or IVa/b a
DETAILS
LOCATIONS
Locations in:
United States, Australia, Belgium, Canada, China, Czechia, France, Germany, Italy, Japan, South Korea, Mexico, Poland, Spain, Sweden, Taiwan, Denmark
| Country (17) | City or Province (112) | Status |
| United States | Paradise Valley Neuromuscular Research Center and Clinic |
RECRUITING
|
| United States | Scottsdale HonorHealth Neurology |
COMPLETED
|
| United States | Los Angeles University of Southern California |
COMPLETED
|
| United States | Palo Alto Stanford University |
COMPLETED
|
| United States | Pasadena Care Access Research |
RECRUITING
|
| United States | Aurora University of Colorado Anschutz Medical Campus |
RECRUITING
|
| United States | New Haven Yale New Haven Hospital |
RECRUITING
|
| United States | Boca Raton FM Clinical Research, LLC South Florida Neurology Associates, P. A. |
RECRUITING
|
| United States | Jacksonville University of Florida Health Jacksonville |
COMPLETED
|
| United States | Port Charlotte Medsol Clinical Research Center Inc |
RECRUITING
|
| United States | Tampa University of South Florida |
RECRUITING
|
| United States | Augusta Augusta University |
COMPLETED
|
| United States | Kansas City University of Kansas Medical Center |
RECRUITING
|
| United States | Burlington Lahey Hospital & Medical Center |
COMPLETED
|
| United States | Saint Louis Washington University School Of Medicine |
COMPLETED
|
| United States | Durham Duke University School of Medicine |
RECRUITING
|
| United States | Cincinnati University of Cincinnati |
COMPLETED
|
| United States | Cleveland Cleveland Clinic |
RECRUITING
|
| United States | Charleston Medical University of South Carolina |
RECRUITING
|
| United States | Cordova Wesley Neurology |
COMPLETED
|
| United States | Dallas UT Southwestern Medical Center |
COMPLETED
|
| United States | Burlington University of Vermont |
COMPLETED
|
| Australia | North Melbourne Melbourne Neurology Group |
COMPLETED
|
| Australia | Southport Gold Coast University Hospital |
RECRUITING
|
| Belgium | Anderlecht ULB Hôpital Erasme |
RECRUITING
|
| Belgium | Brussels Cliniques Universitaires Saint Luc |
RECRUITING
|
| Belgium | Gent AZ Sint-Lucas |
RECRUITING
|
| Belgium | Leuven University Hospitals Leuven |
RECRUITING
|
| Canada | Ottawa The Ottawa Hospital Research Institute |
RECRUITING
|
| Canada | Toronto Toronto General Hospital |
RECRUITING
|
| Canada | Montreal McGill University |
COMPLETED
|
| China | Beijing Beijing Tiantan Hospital, Capital Medical University |
RECRUITING
|
| China | Beijing Xuanwu Hospital ,Capital Medical University |
COMPLETED
|
| China | Beijing Beijing Hospital |
RECRUITING
|
| China | Changchun The First Bethune Hospital of Jilin University |
RECRUITING
|
| China | Fuzhou Fujian Medical University Union Hospital |
COMPLETED
|
| China | Guangzhou The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine |
RECRUITING
|
| China | Jinan Qianfoshan hospital of Shandong Province |
RECRUITING
|
| China | Shanghai Huashan Hospital Fudan University |
RECRUITING
|
| China | Tianjin Tianjin Medical University General Hospital |
RECRUITING
|
| China | Xi'An The Second Affiliated Hospital of Air Force Medical University - Tangdu Hospital |
RECRUITING
|
| Czechia | Brno Neurologie a rehabilitace Skopalíkova |
RECRUITING
|
| Czechia | Praha Vseobecna Fakultní Nemocnice |
RECRUITING
|
| France | Bron Hopital Pierre Wertheimer |
RECRUITING
|
| France | Paris Hopital de la Pitie Salpetriere |
RECRUITING
|
| France | Provence-Alpes-Côte d'Azur Hopital PASTEUR |
RECRUITING
|
| Germany | Berlin NeuroCure Clinical Research Center |
RECRUITING
|
| Germany | Göttingen Universitatsmedizin Gottingen |
RECRUITING
|
| Germany | Leipzig Universitaetsklinikum Leipzig |
COMPLETED
|
| Germany | Lübeck Universitatsklinikum Schleswig Holstein Campus Lubeck |
COMPLETED
|
| Germany | Ulm Universitatsklinikum Ulm |
RECRUITING
|
| Germany | Wiesbaden DKD HELIOS Klinik Wiesbaden, Fachbereich Neurologie |
COMPLETED
|
| Italy | Cefalu Fondazione Istituto G. Giglio |
RECRUITING
|
| Italy | Milano Istituto Neurologico Carlo Besta |
RECRUITING
|
| Italy | Napoli Azienda Ospedaliera Univ.- Università Degli studi della Campania - Luigi Vanvitelli |
RECRUITING
|
| Italy | Pavia IRCCS C. Mondino, Istituto Neurologico Nazionale, Fondazione |
RECRUITING
|
| Italy | Roma Policlinico Universitario Agostino Gemelli |
RECRUITING
|
| Japan | Hanamaki General Hanamaki Hospital |
RECRUITING
|
| Japan | Hiroshima shi Hiroshima University Hospital |
RECRUITING
|
| Japan | Itabashi Ku Teikyo University Hospital |
RECRUITING
|
| Japan | Kawasaki Shi St Marianna University Hospital |
RECRUITING
|
| Japan | Morioka-shi Iwate Medical University Hospital |
RECRUITING
|
| Japan | Nagoya-shi National Hospital Organization Nagoya Medical Center |
RECRUITING
|
| Japan | Niigata Niigata City General Hospital |
RECRUITING
|
| Japan | Nishinomiya-Shi Hyogo College of Medicine Hospital |
RECRUITING
|
| Japan | Sapporo Hokkaido Medical Center |
RECRUITING
|
| Japan | Sendai-City National Hospital Organization Sendai Medical Center |
RECRUITING
|
| Japan | Tokushima Tokushima University Hospital |
RECRUITING
|
| South Korea | Busan Pusan National University Hospital |
RECRUITING
|
| South Korea | Daegu Kyungpook National University Chilgok Hospital |
RECRUITING
|
| South Korea | Daegu Kyungpook National University Hospital |
COMPLETED
|
| South Korea | Seoul Severance Hospital Yonsei University Health System |
RECRUITING
|
| Mexico | Aguascalientes iBiomed Research Unit |
COMPLETED
|
| Mexico | Cuernavaca Consultorio Dr. Miguel Cortes |
RECRUITING
|
| Mexico | Guadalajara Hospital Civil de Guadalajara Fray Antonio Alcalde |
RECRUITING
|
| Poland | Katowice NZOZ Wielospecjalistyczna Poradnia Lekarska 'Synapsis' |
RECRUITING
|
| Poland | Warsaw Centrum Medyczne NeuroProtect |
RECRUITING
|
| Spain | Alicante Hosp. Gral. Univ. de Alicante |
RECRUITING
|
| Spain | Barcelona Hosp. de La Santa Creu I Sant Pau |
RECRUITING
|
| Spain | Barcelona Hosp Univ Vall D Hebron |
RECRUITING
|
| Spain | Barcelona Hosp Clinic de Barcelona |
RECRUITING
|
| Spain | Bilbao Hosp. Univ. de Basurto |
RECRUITING
|
| Spain | Sevilla Hosp. Virgen Macarena |
RECRUITING
|
| Spain | Valencia Hosp. Univ. I Politecni La Fe |
RECRUITING
|
| Sweden | Karlstad Karlstad Central Hospital |
COMPLETED
|
| Sweden | Stockholm Karolinska Universitetssjukhuset Solna |
RECRUITING
|
| Taiwan | Taipei Shin Kong Wu Ho Su Memorial Hospital |
RECRUITING
|
| Taiwan | Taipei Taipei Veterans General Hospital |
RECRUITING
|
| United States | Boston St. Elizabeth Medical Center |
COMPLETED
|
| Belgium | Brugge AZ Sint Jan Brugge Oostende AV |
RECRUITING
|
| China | Changsha Xiangya Hospital Central South University |
RECRUITING
|
| China | Chengdu West China Hospital of Sichuan University |
COMPLETED
|
| China | Hangzhou Sir Run Run Shaw Hospital Zhejiang University School of Medicine |
RECRUITING
|
| China | Jinan Qilu Hospital of Shandong University |
COMPLETED
|
| Czechia | Brno Fakultni nemocnice Brno |
COMPLETED
|
| Denmark | København Ø Rigshospitalet |
COMPLETED
|
| Italy | Catania U.O.P.I. di Psichiatria |
COMPLETED
|
| Italy | Roma Azienda ospedaliera Sant'Andrea di Roma- Università di Roma La Sapienza |
COMPLETED
|
| Japan | Chiba Chiba University Hospital |
COMPLETED
|
| Japan | Kita Gun Kagawa University Hospital |
COMPLETED
|
| Japan | Kumamoto Kumamoto University Hospital |
COMPLETED
|
| Japan | Sapporo Sapporo Medical University Hospital |
COMPLETED
|
| Japan | Tokyo Tokyo Medical University Hospital |
COMPLETED
|
| Poland | Bydgoszcz Neurocentrum Bydgoszcz Sp Z O O |
RECRUITING
|
| Poland | Krakow Centrum Neurologii Klinicznej Krakowska Akademia Neurologii |
RECRUITING
|
| Poland | Lublin Prywatny Gabinet Lekarski |
RECRUITING
|
| Spain | Sevilla Hosp. Virgen Del Rocio |
COMPLETED
|
| Taiwan | Taichung China Medical University Hospital |
COMPLETED
|
| United States | Columbus The Ohio State University |
COMPLETED
|
| Denmark | Aalborg Aalborg University Hospital |
COMPLETED
|
| France | Grenoble CHU Grenoble |
COMPLETED
|
| France | Provence-Alpes-Côte d'Azur Hopital PASTEUR |
COMPLETED
|
Geo Locations
33.53115, -111.94265
33.50921, -111.89903
34.05223, -118.24368
37.44188, -122.14302
34.14778, -118.14452
39.72943, -104.83192
41.30815, -72.92816
26.3669, -80.13033
30.33218, -81.65565
26.97617, -82.09064
27.94752, -82.45843
33.47097, -81.97484
39.11417, -94.62746
42.50482, -71.19561
38.62727, -90.19789
35.99403, -78.89862
39.12713, -84.51435
41.4995, -81.69541
32.77657, -79.93092
35.15565, -89.7762
32.78306, -96.80667
44.47588, -73.21207
-37.80132, 144.95822
-27.96724, 153.39796
50.83619, 4.31454
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51.05, 3.71667
50.87959, 4.70093
45.41117, -75.69812
43.70011, -79.4163
45.50884, -73.58781
39.9075, 116.39723
39.9075, 116.39723
39.9075, 116.39723
43.88, 125.32278
26.06139, 119.30611
23.11667, 113.25
36.66833, 116.99722
31.22222, 121.45806
39.14222, 117.17667
34.25833, 108.92861
49.19522, 16.60796
50.08804, 14.42076
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43.6960355, 7.2655896
52.52437, 13.41053
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39.38333, 141.11667
34.4, 132.45
35.74893, 139.71497
35.52056, 139.71722
39.7, 141.15
35.18147, 136.90641
37.88637, 139.00589
34.71562, 135.33199
43.06667, 141.35
38.26667, 140.86667
34.06667, 134.56667
35.10278, 129.04028
35.87028, 128.59111
35.87028, 128.59111
37.566, 126.9784
21.88234, -102.28259
18.9261, -99.23075
20.66682, -103.39182
50.25841, 19.02754
52.22977, 21.01178
38.34517, -0.48149
41.38879, 2.15899
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41.38879, 2.15899
43.26271, -2.92528
37.38283, -5.97317
39.46975, -0.37739
59.3793, 13.50357
59.33258, 18.0649
25.04776, 121.53185
25.04776, 121.53185
42.35843, -71.05977
51.20892, 3.22424
28.19874, 112.97087
30.66667, 104.06667
30.29365, 120.16142
36.66833, 116.99722
49.19522, 16.60796
55.67594, 12.56553
37.49223, 15.07041
41.89193, 12.51133
35.6, 140.11667
34.2939708, 134.1237443
32.80589, 130.69182
43.06667, 141.35
35.6895, 139.69171
53.1235, 18.00762
50.06143, 19.93658
51.25, 22.56667
37.38283, -5.97317
24.1469, 120.6839
39.96118, -82.99879
57.048, 9.9187
45.16667, 5.71667
43.6960355, 7.2655896
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