A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease (FUZION CD)
Last Updated May 17, 2025
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CR109189
OVERVIEW
-
Sexes Eligible for Study
all -
Age
years -
Phase
phase 3 -
Sites
Sites -
Status
Recruiting
SUMMARY
The purpose of this study to evaluate the clinical efficacy of guselkumab in fistulizing, perianal Crohn's disease and to assess the overall safety of guselkumab.
CONDITIONS
- Fistulizing Crohns Disease
- Perianal Crohns Disease
ELIGIBILITY
Inclusion Criteria:
* Must have a diagnosis of Crohn's disease with a minimum duration of at least 3 months
* Has at least one active draining perianal fistula as a complication of Crohn's disease, confirmed by screening magnetic resonance imaging (MRI) results
* Has previousl
DETAILS
LOCATIONS
Locations in:
United States, Australia, Belgium, Canada, Czechia, France, Germany, Greece, Hungary, Israel, Italy, Japan, Jordan, South Korea, Netherlands, Poland, Portugal, Saudi Arabia, Spain, Taiwan, Türkiye, United Kingdom, Egypt
| Country (23) | City or Province (153) | Status |
| United States | Birmingham University of Alabama at Birmingham |
COMPLETED
|
| United States | Naples Gastroenterology Group Of Naples |
RECRUITING
|
| United States | Orlando AdventHealth Medical Group Blood & Marrow Transplant at Orlando |
RECRUITING
|
| United States | Kansas City Kansas University Medical Center |
RECRUITING
|
| United States | Louisville University of Louisville |
RECRUITING
|
| United States | New York Mount Sinai School of Medicine |
RECRUITING
|
| United States | Oklahoma City Digestive Disease Specialists Inc |
COMPLETED
|
| United States | Germantown Gastro One |
RECRUITING
|
| United States | Tyler Tyler Research Institute, LLC |
RECRUITING
|
| United States | Seattle Swedish Medical Center |
RECRUITING
|
| Australia | Adelaide Flinders Medical Centre |
RECRUITING
|
| Australia | Fitzroy St Vincent's Hospital - Melbourne |
RECRUITING
|
| Australia | Murdoch Fiona Stanley Hospital |
RECRUITING
|
| Australia | Newtown Royal Prince Alfred Hospital |
RECRUITING
|
| Australia | North Terrace Royal Adelaide Hospital |
RECRUITING
|
| Australia | Parkville Royal Melbourne Hospital |
RECRUITING
|
| Australia | Perth Royal Perth Hospital |
RECRUITING
|
| Australia | South Brisbane Mater Hospital |
RECRUITING
|
| Belgium | Leuven UZ Leuven |
RECRUITING
|
| Belgium | Liege CHU Sart Tilman |
RECRUITING
|
| Canada | Edmonton University of Alberta- Ziedler Ledcor Centre |
RECRUITING
|
| Canada | London London Health Sciences Centre |
RECRUITING
|
| Canada | Toronto Mount Sinai Hospital |
RECRUITING
|
| Canada | Montreal McGill University Health Centre |
RECRUITING
|
| Czechia | Ceske Budejovice Nemocnice Ceske Budejovice a s |
RECRUITING
|
| France | Neuilly-sur-Seine Clinique Ambroise Pare |
RECRUITING
|
| France | Pierre-Benite Centre Hospitalier Lyon Sud |
RECRUITING
|
| France | Rennes CHRU Hopital de Pontchaillou |
RECRUITING
|
| France | Vandoeuvre les Nancy CHRU Nancy Brabois |
RECRUITING
|
| Germany | Berlin Charite - Campus Mitte |
RECRUITING
|
| Germany | Frankfurt JWG-University Hospital |
RECRUITING
|
| Germany | Mannheim Universitaetsklinikum Mannheim |
RECRUITING
|
| Greece | Athens Evangelismos General Hospital of Athens |
RECRUITING
|
| Greece | Athens Hippokration Hospital |
RECRUITING
|
| Greece | Heraklion University Hospital of Heraklion |
RECRUITING
|
| Greece | Patras Patras University Hospital |
RECRUITING
|
| Hungary | Budapest Magyar Honvedseg Egeszsegugyi Kozpont |
RECRUITING
|
| Hungary | Budapest Semmelweis Egyetem |
RECRUITING
|
| Hungary | Budapest Semmelweis Egyetem |
RECRUITING
|
| Israel | Haifa Rambam Medical Center |
RECRUITING
|
| Israel | Jerusalem Shaare Zedek Medical Center |
RECRUITING
|
| Israel | Petah Tikva Rabin Medical Center Beilinson Campus |
RECRUITING
|
| Italy | Milano Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico |
RECRUITING
|
| Italy | Negrar ( Ve) Ospedale Classificato Equiparato Sacro Cuore Don Calabria di Negrar |
RECRUITING
|
| Italy | Pisa Azienda Ospedaliera Universitaria Pisana |
RECRUITING
|
| Italy | San Giovanni Rotondo Casa Sollievo della Sofferenza |
RECRUITING
|
| Japan | Abiko KOKIKAI Tokatsu Tsujinaka Hospital |
RECRUITING
|
| Japan | Chikushino-shi Fukuoka University Chikushi Hospital |
RECRUITING
|
| Japan | Fukuoka-ken Kitakyushu Municipal Medical Center |
RECRUITING
|
| Japan | Hiroshima shi Hiroshima University Hospital |
RECRUITING
|
| Japan | Kagoshima Sameshima Hospital |
RECRUITING
|
| Japan | Kashihara Nara Medical University Hospital |
RECRUITING
|
| Japan | Kashiwa Tsujinaka Hospital Kashiwanoha |
RECRUITING
|
| Japan | Nagasaki Nagasaki University Hospital |
RECRUITING
|
| Japan | Nishinomiya The Hospital of Hyogo College of Medicine |
RECRUITING
|
| Japan | Shinjuku-ku Tokyo Yamate Medical Center |
RECRUITING
|
| Japan | Shizuoka Matsuda Hospital |
RECRUITING
|
| Japan | Suita Osaka University Hospital |
RECRUITING
|
| Japan | Tokyo Kyorin University Hospital |
RECRUITING
|
| Japan | Toyota Ieda Hospital |
RECRUITING
|
| Japan | Tsu Mie University Hospital |
RECRUITING
|
| Japan | Yokkaichi Yokkaichi Hazu Medical Center |
RECRUITING
|
| Jordan | Amman The Speciality Hospital (TSH) / Advanced Clinical Center |
RECRUITING
|
| Jordan | Amman Jordan University Hospital |
RECRUITING
|
| Jordan | Amman Abdali Hospital |
RECRUITING
|
| Jordan | Irbid Irbid Specialty Hospital |
RECRUITING
|
| Jordan | Irbid King Abdullah University Hospital |
RECRUITING
|
| South Korea | Seoul Seoul National University Hospital |
RECRUITING
|
| South Korea | Seoul Gangnam Severance Hospital, Yonsei University Health System |
RECRUITING
|
| Netherlands | Amsterdam Academisch Medisch Centrum Universiteit van Amsterdam |
RECRUITING
|
| Netherlands | Nijmegen Radboudumc |
RECRUITING
|
| Netherlands | Utrecht UMC Utrecht |
COMPLETED
|
| Poland | Bialystok Gastromed Kralisz Romatowski Stachurska Sp. j. |
RECRUITING
|
| Poland | Krakow Centrum Medyczne Promed |
RECRUITING
|
| Poland | Rzeszow Centrum Medyczne Medyk |
RECRUITING
|
| Poland | Szczecin Twoja Przychodnia - Szczecinskie Centrum Medyczne |
RECRUITING
|
| Poland | Warszawa WIP Warsaw IBD Point Profesor Kierkus |
RECRUITING
|
| Poland | Wroclaw Melita Medical Sp. z o.o. |
RECRUITING
|
| Portugal | Porto H. Santo António - Centro Hospitalar do Porto |
RECRUITING
|
| Saudi Arabia | Dammam King Fahad Specialist hospital |
RECRUITING
|
| Saudi Arabia | Jeddah King Abdulaziz Medical City |
RECRUITING
|
| Saudi Arabia | Riyadh King Saud University Medical City |
RECRUITING
|
| Saudi Arabia | Riyadh King Faisal Specialist Hospital & Research Center |
RECRUITING
|
| Spain | Barcelona Hosp Clinic de Barcelona |
RECRUITING
|
| Spain | Ferrol Hosp. Arquitecto Marcide |
RECRUITING
|
| Spain | Madrid Hosp. Univ. de La Princesa |
RECRUITING
|
| Spain | Majadahonda Hosp. Univ. Pta. de Hierro Majadahonda |
RECRUITING
|
| Spain | Sevilla Hosp. Virgen Macarena |
RECRUITING
|
| Spain | Vigo Hosp. Alvaro Cunqueiro |
RECRUITING
|
| Spain | Zaragoza Hosp. Univ. Miguel Servet |
RECRUITING
|
| Taiwan | Changhua Changhua Christian Hospital |
RECRUITING
|
| Taiwan | Taichung Taichung Veterans General Hospital |
RECRUITING
|
| Taiwan | Taipei City National Taiwan University Hospital |
RECRUITING
|
| Taiwan | Taoyuan City Chang Gung Memorial Hospital Linkou Branch |
RECRUITING
|
| Türkiye | Ankara Gazi University Medical Faculty |
RECRUITING
|
| Türkiye | Istanbul Istanbul University Cerrahpasa Medical Faculty |
RECRUITING
|
| Türkiye | Istanbul Acibadem Kozyatagi Hospital |
RECRUITING
|
| Türkiye | İzmir Ege University Medical Faculty |
RECRUITING
|
| Türkiye | Mersin Mersin University Medical Faculty Hospital |
RECRUITING
|
| United Kingdom | Hull Hull University Teaching Hospitals NHS Trust |
RECRUITING
|
| United Kingdom | London London North West University Healthcare NHS Trust |
RECRUITING
|
| United Kingdom | London St George's University Hospital NHS Foundation Trust |
RECRUITING
|
| United Kingdom | Newcastle Upon Tyne Newcastle upon Tyne Hospitals NHS Foundation Trust |
RECRUITING
|
| United Kingdom | Salford Pennine Acute Hospitals NHS Trust |
RECRUITING
|
| United States | Saint Louis Washington University School Of Medicine |
COMPLETED
|
| Germany | Ulm Universitaetsklinikum Ulm |
RECRUITING
|
| Japan | Nagoya Nagoya University Hospital |
RECRUITING
|
| Spain | Girona Hosp. Univ. Dr. Josep Trueta |
RECRUITING
|
| United States | New Haven Yale University |
COMPLETED
|
| United States | Miami University of Miami |
COMPLETED
|
| United States | Lexington University of Kentucky Chandler Medical Center |
COMPLETED
|
| United States | Nashville Vanderbilt University Medical Center |
COMPLETED
|
| Australia | Liverpool Liverpool Hospital |
COMPLETED
|
| Belgium | Bruxelles Hopital Erasme |
COMPLETED
|
| Belgium | Genk Ziekenhuis Oost-Limburg |
COMPLETED
|
| Canada | Halifax Nova Scotia Health Authority |
COMPLETED
|
| Czechia | Praha 9 ISCARE a.s. |
COMPLETED
|
| Egypt | Alexandria Alexandria University Hospital |
RECRUITING
|
| Egypt | Cairo National Hepatology and Tropical Medicine Research Institute |
RECRUITING
|
| Egypt | Cairo Ain Shams University Hospital |
RECRUITING
|
| Egypt | Giza Cairo university |
RECRUITING
|
| France | Nice CHU de Nice Hopital de l Archet |
COMPLETED
|
| France | Paris Hopital Saint Joseph |
COMPLETED
|
| Germany | Kiel Universitatsklinikum Schleswig Holstein Kiel |
COMPLETED
|
| Greece | Athens Attica Alexandra General Hospital of Athens |
RECRUITING
|
| Greece | Athens Sotiria General State Hospital of Chest Diseases |
RECRUITING
|
| Greece | Larissa University Hospital Of Larissa |
RECRUITING
|
| Greece | Thessaloniki Hippokration Hospital |
RECRUITING
|
| Hungary | Budapest Semmelweis Egyetem |
COMPLETED
|
| Hungary | Pecs Pecsi Tudomanyegyetem Orvostudomanyi Es Egeszsegtudomanyi Centrum, I. Belgyogyaszati Klinika |
COMPLETED
|
| Hungary | Szeged Szegedi Tud Egyetem Szent Gyorgyi Albert Klin Kozp |
RECRUITING
|
| Israel | Afula Haemek Medical Center |
RECRUITING
|
| Italy | RHO Azienda Ospedaliera G.Salvini Ospedale di Rho |
COMPLETED
|
| Italy | Roma Policlinico Universitario Agostino Gemelli |
RECRUITING
|
| Italy | Rozzano Istituto Clinico Humanitas |
RECRUITING
|
| Japan | Fukuoka Fukuoka University Hospital |
COMPLETED
|
| Japan | Hukuoka Hospital of the University of Occupational and Enviromental Health |
COMPLETED
|
| Japan | Nagoya Kojunkai Daido Clinic |
COMPLETED
|
| Japan | Okayama Okayama University Hospital |
RECRUITING
|
| Japan | Osaka Kinshukai Infusion Clinic |
COMPLETED
|
| Japan | Sakai JOHAS Osaka Rosai Hospital |
COMPLETED
|
| Japan | Sapporo Sapporo Higashi Tokushukai Hospital |
COMPLETED
|
| Japan | Yokohama Yokohama Municipal Citizen's Hospital |
COMPLETED
|
| South Korea | Busan Inje University Haeundae Paik Hospital |
COMPLETED
|
| South Korea | Daegu Yeungnam University Hospital |
COMPLETED
|
| South Korea | Gyeonggi-do Seoul National University Bundang Hospital |
COMPLETED
|
| Netherlands | Rotterdam Erasmus MC |
COMPLETED
|
| Poland | Lodz Centrum Medyczne Med Gastr |
RECRUITING
|
| Poland | Torun GASTROMED Kopon Zmudzinski i wspolnicy SP j Specjalistyczne Centrum Gastrologii i Endoskopii |
RECRUITING
|
| Poland | Wroclaw Centrum Medyczne Oporow |
RECRUITING
|
| Portugal | Braga Uls Braga - Hosp. Braga |
RECRUITING
|
| Portugal | Lisboa Uls Sao Jose - Hosp. Sto Antonio Dos Capuchos |
COMPLETED
|
| United Kingdom | London Guys and St Thomas NHS Foundation Trust |
RECRUITING
|
Geo Locations
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